Results 91 to 100 of about 640,482 (311)

Measuring place identity in public open spaces

open access: yes, 2017
There is a growing body of evidence that indicates that for creating civic consciousness and sustaining urban identity and memory people need civic interaction and social reconciliation, which are promoted by public open spaces.
Polat, Sibel, Dostoğlu, Neslihan
core   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

The evolutionary ‘waves’ of place-shaping: pre, during and post recession

open access: yes, 2011
This paper is concerned with the evolution of place-shaping over the past decade or so and its potential future direction, specifically relating to a UK context but with varying aspects of resonance internationally.
Pugalis, L, Pugalis, Lee
core  

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

The Role of Urban Design in Enhancing Humanization in Libyan Cities Through Place Making and Developing Public Spaces

open access: yesPLANARCH - Design and Planning Research
Most countries globally confront the challenge of escalating population densities, accompanied by an increase in private transportation. This phenomenon has led to the degradation of urban environments in these nations, with a severe scarcity of urban ...
Ali Issa   +3 more
doaj   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

open access: yesFEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe   +5 more
wiley   +1 more source

VR/Urban : spread.gun - design process and challenges in developing a shared encounter for media façades

open access: yes, 2010
Designing novel interaction concepts for urban environments is not only a technical challenge in terms of scale, safety, portability and deployment, but also a challenge of designing for social configurations and spatial settings.
Fischer, P. T.   +8 more
core   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Predicting the Impact of Urban Development on Locals’ Place Attachment in Peripheral Settlements [PDF]

open access: yesUrbanism. Arhitectura. Constructii
As urban development reshapes cityscapes, residents in peripheral settlements face challenges in maintaining Place Attachment. This study examines the potential disruption of Place Dependence, Place Identity, and Place Affection—core components of Place ...
Farid Nazaruddin   +2 more
doaj  

Place centric design of public displays for libraries

open access: yes
Conception centrée sur le lieu des affichages publics dans les bibliothèques Les bibliothèques publiques sont des tiers lieux vivants accueillant des personnes de toutes les tranches de la société. En plus d’offrir de vastes collections de documents, elles accueillent un large éventail d’événements : lectures publiques, clubs, activités
openaire   +2 more sources

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