Results 91 to 100 of about 3,403,124 (306)
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Proposed upgrading works of Cameron Highlands public district library for Perbadanan Perpustakaan Awam Pahang (PPAP) at 39000 Tanah Rata, Cameron Highlands, Pahang Darul Makmur / Norain Zulaika Abu Hassan [PDF]
The library is very important in our life and it has become almost part of our life. Library is so close to everyone either for kids,teenagers,usually of the are students,adults and veteran.
Abu Hassan, Norain Zulaika
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CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Mediated city: Annual review 2012 [PDF]
The research projects under Mediated City explore questions that traverse through various disciplines to create new knowledge. Here, design catalyses changes in people’s practices to cross boundary domains, such as art, business, geospatial science ...
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Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Ideas, Artifacts, and Facilities: Information as a Common-Pool Resource [PDF]
The goal of this paper is to summarize the lessons learned from a large body of international, interdisciplinary research on common-pool resources (CPRs) in the past 25 years and consider its usefulness in the analysis of scholarly information as a ...
Hess, Charlotte, Ostrom, Elinor
core +2 more sources
Molecular cancer prevention: Intercepting disease
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco +2 more
wiley +1 more source
Most countries globally confront the challenge of escalating population densities, accompanied by an increase in private transportation. This phenomenon has led to the degradation of urban environments in these nations, with a severe scarcity of urban ...
Ali Issa +3 more
doaj +1 more source
Political drivers of and barriers to Public-Private Partnerships: The role of political involvement [PDF]
The application and design of public-private partnerships between the extremes of purely public or purely private task fulfilment in public services is, in practice, subject to political processes.
Gawel, Erik
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Shaping the criminal justice system: the role of those supported by Criminal Justice Service [PDF]
In Scotland, the development and delivery ofpersonalised social work services has been part of a wider public service reform agenda, building on Changing lives: report of the 21st century review of social work (Scottish Executive, 2006).
Lightowler, C., Weaver, Beth
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