Results 71 to 80 of about 3,403,124 (306)

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

EU Services Directive - Design Approaches for Romania [PDF]

Modernizing public administration is the basis for implementation of the EU directive, and in order to ensure this successfully, collaborative procedures between administrative institutions and countries must be put in place and further developed.
Catalin Ionut SILVESTRU, Codrin NISIOIU, Cosmin RENTEA, Jorn von LUCKE   +3 more
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Determinant Factors of Pneumonia Among Toddlers [PDF]

, 2018
Pneumonia still becomes a public health problems that causing pain and death on toddlers. There are many factors which may influence the increase of pneumonia incidence on toddlers, from the aspect of kid individuals and house anvironment such as ...
Dwi Jatmika, Septian Emma, Handari, D. R. (Dwi), Maulana, M. (Muchsin), Sunarti, H. (Hermin)   +3 more
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Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion

Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana, Mariana Maschietto, Daniela Paz Leal, Ricardo de Santos de Oliveira, Mayara Ferreira Euzébio, Antonio Carlos dos Santos, Luciano Neder, Carlos Alberto Scrideli, Elvis Terci Valera   +8 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

The built environment and place attachment: Insights from Japanese cities

Preventive Medicine Reports
Objective: Place attachment plays an important role in individuals' health and well-being. Understanding the associations between urban design attributes and place attachment can inform strategies to promote place attachment.
Jiuling Li, Mohammad Javad Koohsari, Andrew T. Kaczynski, Ryo Tanimoto, Reo Watanabe, Tomoki Nakaya, Yufeng Luo, Jing Zhao, Akitomo Yasunaga, Koichiro Oka, Tomoya Hanibuchi   +10 more
doaj   +1 more source

Jogja Eco2 Cities: Konsep Tata Kota Untuk Mewujudkan YOGYAKARTA Sebagai Kota Ecologies Dan Economics Melalui Integrasi Transportasi Masal [PDF]

, 2014
Civil growth level in Jogjakarta regency appearently brings a positive impact on the economic growth level. Economic growth level in a certain area also always give negative impact, like a public stagnation and air polution.
Nur Utari, Khoirunisa Ulya, Sarifudin, R. (Rochmat), Wibowo, A. K. (Achmad)   +2 more
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EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Introducing Design Thinking in Social Innovation and in the Public Sector: a design based learning framework

European Public & Social Innovation Review, 2017
Design Thinking (DT) is becoming a mantra in the different areas of innovation: including SI and Public sector (Manzini&Rizzo, 2011; Deserti&Rizzo, 2015).
Francesca Rizzo,, Alessandro Deserti, , Onur Cobanli   +2 more
doaj   +1 more source

Competition and cost overruns. Optimal misspecification of procurement contracts [PDF]

Most cases of cost overruns in public procurement are related to important changes in the initial project design. This paper deals with the problem of design specification in public procurement and provides a rationale for design misspecification.
Juan J. Ganuza
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