Results 51 to 60 of about 612,715 (216)

How Do Public Perceptions Affect the Security of Connected Places? A Systematic Literature Review

Information
This systematic literature review explores the scholarly debate around public perceptions and behaviors in the context of cybersecurity in connected places. It reveals that, while many articles highlight the importance of public perceptions and behaviors
Agnieszka Dutkowska-Zuk, Joe Bourne, Chengyuan An, Xuan Gao, Oktay Cetinkaya, Peter Novitzky, Gideon Ogunniye, Rachel Cooper, David De Roure, Julie McCann, Jeremy Watson, Tim Watson, Eleri Jones   +12 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Policy entrepreneurship in collaborative governance: transformative innovation in Catalonia’s sustainability transition

Policy Design and Practice
There is increasing recognition that public sectors in Western countries alone cannot tackle complex societal challenges. However, detailed research on the role of public agents in implementing collaborative approaches remains limited.
Míriam Acebillo-Baqué, Diana Velasco, Alejandra Boni   +2 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Cross-cultural public space inclusivity: a multidimensional analysis of user satisfaction in Nottingham, Jeddah, and Lucknow

Frontiers in Sustainable Cities
Urban public spaces play a central role in supporting social interaction, inclusivity, and urban liveability, yet their performance is shaped by cultural, social, and governance contexts.
Adiba Shafique, Faynana Alawadi, Nazish Abid, Saja Jamil Alamoush, Mouhanad Bawadkji   +4 more
doaj   +1 more source

Public poll for support 100 % smoke free area regulation to protect children from secondhand smoke exposure in big city on 8 provinces in Indonesia

Tobacco Induced Diseases, 2018
Objective Support Goverment and parliament to enact a national regulation about 100 % smoke free area for protect children from smoke exposure on all place. Methods 1. The study design was cross-sectional with data collection conducted during the months
Tri Ningsih
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source