Results 51 to 60 of about 640,482 (311)
BuildingsWith the rise of green building and biophilic design, how sports venues enhance users’ place attachment through natural design features has become a critical interdisciplinary research topic in architecture and environmental psychology. This study adopts
Zhihao Zhang +3 more
doaj +1 more source
Strengthening Community Sense of Place through Placemaking
Urban Planning, 2019 The concept of community involvement and the effect that the act of “making” has on the community itself is a key consideration in the placemaking discussion (Project for Public Spaces, 2015a; Silberberg, Lorah, Disbrow, & Muessig, 2013).
Peter J. Ellery, Jane Ellery
doaj +1 more source
Participatory place branding through design: the case of Dunga beach in Kisumu, Kenya
, 2015 For place branding to reach long-term commitment and legitimacy a large number of stakeholders needs to be involved. This calls for innovative ways of approaching the process itself, permitting it to be participatory and changeable.
Kraff, Helena +3 more
core +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Public Diplomacy, Place Branding, and Refugee Settlement
, 2021 Background Nowadays, not only countries but also cities and regions communicate directly with residents in other countries using public diplomacy. Public diplomacy includes all official efforts to convince targeted sectors of foreign opinion to support ...
Rauhut Kompaniets, Olga, Rauhut, Daniel
core
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Briefing: Blue Carpet, Newcastle, UK: public realm design decision making from a user perspective
, 2012 Public realm design decision making can be complex and variable with unpredictable results. Analysis of decision making, including the principles applied and the role of key players can help clarify ingredients for success.
Paterson, Elaine
core +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source