Results 61 to 70 of about 3,403,124 (306)

Optimal Alignments for Designing Urban Transport Systems: Application to Seville [PDF]

, 2019
The achievement of some of the Sustainable Development Goals (SDGs) from the recent 2030 Agenda for Sustainable Development has drawn the attention of many countries towards urban transport networks. Mathematical modeling constitutes an analytical tool
Marseglia, Guido, Medaglia, Carlo Maria, Mesa López-Colmenar, Juan Antonio, Ortega Riejos, Francisco Alonso   +3 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

How Do Public Perceptions Affect the Security of Connected Places? A Systematic Literature Review

Information
This systematic literature review explores the scholarly debate around public perceptions and behaviors in the context of cybersecurity in connected places. It reveals that, while many articles highlight the importance of public perceptions and behaviors
Agnieszka Dutkowska-Zuk, Joe Bourne, Chengyuan An, Xuan Gao, Oktay Cetinkaya, Peter Novitzky, Gideon Ogunniye, Rachel Cooper, David De Roure, Julie McCann, Jeremy Watson, Tim Watson, Eleri Jones   +12 more
doaj   +1 more source

Public poll for support 100 % smoke free area regulation to protect children from secondhand smoke exposure in big city on 8 provinces in Indonesia

Tobacco Induced Diseases, 2018
Objective Support Goverment and parliament to enact a national regulation about 100 % smoke free area for protect children from smoke exposure on all place. Methods 1. The study design was cross-sectional with data collection conducted during the months
Tri Ningsih
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Policy entrepreneurship in collaborative governance: transformative innovation in Catalonia’s sustainability transition

Policy Design and Practice
There is increasing recognition that public sectors in Western countries alone cannot tackle complex societal challenges. However, detailed research on the role of public agents in implementing collaborative approaches remains limited.
Míriam Acebillo-Baqué, Diana Velasco, Alejandra Boni   +2 more
doaj   +1 more source

Place centric design of public displays for libraries

, 2021
Public libraries are lively third places welcoming people from all levels of society. In addition to offering extensive collections of documents, they host a wide range of events: from public readings, clubs, to hands-on participatory activities. Each of these events sparks the curation and creation of a variety of content by librarians and patrons ...
openaire   +1 more source

Cohesion policy in the light of place-based innovation support: New approaches in multi-actors, decentralised regional settings with bottom-up strategies? [PDF]

According to the Barca report and the OECD, the place-based development approach is a new paradigm of regional policy. It underlines the necessity to distribute policy design and implementation among different policy levels in order to tailor policy ...
Koschatzky, Knut, Stahlecker, Thomas
core  

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Visual Asset Design Promotion Ciwidey Gambung Tea Plantation Agrotourism Area [PDF]

, 2019
Agro Tourism The Gambung Ciwidey tea plantation is one of the agrotourism in Bandung Regency. This agrotourism is located in the Gambung tea plantation. It is unfortunate with the many potentials there but not many people know about the existence of this
Nurusholih, S. (Sonson ), Permana, G. (Gandara )   +1 more
core