Results 111 to 120 of about 3,391,421 (303)

Health and wellbeing impacts of housing converted from non-residential buildings: A mixed-methods exploratory study in London, UK

Wellbeing, Space and Society
Housing quality is a determinant of health, wellbeing and inequities. Since 2013, changes to Permitted Development Rights (PDR) allow conversions of non-residential buildings into housing without planning permission in England.
Helen Pineo, Ben Clifford, Max Eyre, Robert W. Aldridge   +3 more
doaj   +1 more source

Cohesion policy in the light of place-based innovation support: New approaches in multi-actors, decentralised regional settings with bottom-up strategies? [PDF]

According to the Barca report and the OECD, the place-based development approach is a new paradigm of regional policy. It underlines the necessity to distribute policy design and implementation among different policy levels in order to tailor policy ...
Koschatzky, Knut, Stahlecker, Thomas
core  

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

‘Liquid’ equilibria. New semantics for public spaces in the Apennines

Ri-vista: Ricerche per la Progettazione del Paesaggio
The proposed contribution investigates the role of public space design for the management and regeneration of the river system in Apennine areas: in an environmental crisis and increasing abandonment scenario, water stands as a central issue of critical
Giulia Azzini
doaj   +1 more source

EU Services Directive - Design Approaches for Romania [PDF]

Modernizing public administration is the basis for implementation of the EU directive, and in order to ensure this successfully, collaborative procedures between administrative institutions and countries must be put in place and further developed.
Catalin Ionut SILVESTRU, Codrin NISIOIU, Cosmin RENTEA, Jorn von LUCKE   +3 more
core  

Prayer room design in transit area [PDF]

, 2015
The prayer room in transit area such as shopping mall, an exhibition hall,an airport,or other public building is an intervention to its surrounding and a welcoming place to find shelter or stop briefly, as a place of transit in our routine life.
Daud, Lutfi, Hamzah, Noor Hazwani, Ismail, Sumarni, Mohd Yunus, Mohd. Yazid, Nurshamiela, Rahayu Intan, ul Hussain, Mohd Amir, Utaberta, Nangkula   +7 more
core  

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Bir “Üst Sokak” Önerisinin Tasarım Süreci

Düzce Üniversitesi Bilim ve Teknoloji Dergisi, 2014
Kamusal alanlar, bireyin ilk mekan algısını belirleyen, mekana dair deneyim ve anıları şekillendiren bir süreci tanımlamaktadır. Bu alanlar, kamu yapıları ve açık alanlar ile birlikte çevre ve sosyal davranışların sürekli etkileşim içinde olduğu ...
Özgür YERLİ, Sinem ÖZDEDE, Sertaç KAYA, Simge ÖZDAL OKTAY, İrfan DURSUN   +4 more
doaj  

Connecting the Dots: A Healthy Community Leader's Guide to Understanding the Nonprofit Hospital Community Benefit Requirements [PDF]

, 2015
Imagine a healthy community as a connect-the-dots landscape painting. Each "dot" has its place and purpose: affordable housing, a vibrant economy, safe streets and public transportation, a high quality public education system, easy access to fresh food ...
C. J. Eisenbarth Hager
core  

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source