Results 91 to 100 of about 32,031,316 (275)

Lactiplantibacillus Plantarum GUANKE Alleviates Allergic Asthma by Restricting Monocyte‐to‐DC Differentiation Via Microbiota‐Associated IAA

Advanced Science, EarlyView.
Lactiplantibacillus plantarum GUANKE remodels the indigenous gut microbiota and is associated with microbiota‐dependent restoration of circulating IAA. IAA treatment attenuates JAK3‐STAT3 and Jag1‐Notch4‐Hey1 signaling and reduces CX3CR1+Ly6C− monocytic precursor generation and pulmonary CD11b+ DC accumulation, together with reduced Th2 inflammation ...
Yujia He, Jielan Mi, Zhiping Zhao, Xiao Zhang, Zhihan Yang, Kun Yue, Yuanming Huang, Liqiong Song, Xiaoting Wen, Jianguo Xu, Zhihong Ren   +10 more
wiley   +1 more source

Early Retinal UCHL1 Dysregulation Coupled With Synaptic Loss Reflects Alzheimer's Disease Severity

Advanced Science, EarlyView.
This study identifies synapse‐enriched deubiquitinase UCHL1 as an early Aβ‐responsive regulator of retinal synaptopathy in Alzheimer's disease. Retinal UCHL1 loss accompanies excitatory synapse degeneration, p75NTR activation, and neuroinflammation, and predicts Braak stage and cognitive decline. Aβ42 fibrils trigger synaptic and UCHL1 depletion before
Altan Rentsendorj, Jean‐Philippe Vit, Alexandre Hutton, Yosef Koronyo, Saba Shahin, Edward Robinson, Ernesto Barron, Anthony Rodriguez, Ousman Jallow, Julia Sheyn, Bhakta Prasad Gaire, Lalita Subedi, Miyah R. Davis, Barathan Gnanabharathi, Alexander V. Ljubimov, Stuart L. Graham, Vivek K. Gupta, Mehdi Mirzaei, Debra Hawes, Katlin Silm, Keith L. Black, Lon S. Schneider, Alfredo A. Sadun, Jesse G. Meyer, Dieu‐Trang Fuchs, Maya Koronyo‐Hamaoui   +25 more
wiley   +1 more source

Influence of Public Service Media Consumption on Citizens’ Perceptions of the Need for Public Media: The Moderating Role of Political Ideology

International Journal of Communication, 2023
Public service media (PSM) are under constant pressure to prove their public value and cultural impact. Ultimately, beyond theoretical arguments and regulatory actions, citizens’ perceptions and evaluations of PSM stand at the center of its legitimacy ...
Marcela Campos Rueda
doaj  

From public service broadcasting to public service media

, 2011
This book is written by media scholars from all over Europe who are members of the Euromedia Research Group. What unites the group is the joint interest of its members in the analysis of media structures and media policy in Europe against the background of contemporary communication theories and concepts.
Haenens, Leen d', Sousa, Helena, Hultén, Olof   +2 more
openaire   +1 more source

Automated Extraction of Multicomponent Alloy Data Using Large Language Models for Sustainable Design

Advanced Science, EarlyView.
A large language model (LLM) based pipeline is developed to automatically extract a comprehensive and accurate multicomponent alloy database from literature corpus. The extracted dataset is integrated with sustainability indicators to identify potential alloys that outperform existing industrial benchmark materials in terms of both performance and ...
Aravindan Kamatchi Sundaram, Mohit Chakraborty, Sai Mani Kumar Devathi, B. Pabitramohan Prusty, Rohit Batra   +4 more
wiley   +1 more source

Molecular and Cellular Hallmarks of Age‐Related Vestibular Hair Cell Degeneration

Advanced Science, EarlyView.
This study utilizes single‐cell RNA‐seq transcriptomes, advanced imaging, and electrophysiology to examine universal and cell‐type‐specific aging signatures of vestibular hair cells. The study shows that impaired hair bundle function is a key driver of age‐related vestibular dysfunction.
Samadhi Kulasooriya, Huizhan Liu, Sarath Vijayakumar, Celia Bloom, Zhenhang Xu, Shu Tu, Benjamin J. Borgmeier, Mi Zhou, Litao Tao, Bechara Kachar, David Z. He   +10 more
wiley   +1 more source

Circular on Guidelines on the Public Service Commission (State Corporations and Public Universities) Disciplinary Appeal Procedures 2024 [PDF]

The Public Service Commission has, pursuant to provisions of sections 74 and 75 of the PSC Act of 2017 and regulation 68 of the PSC Regulations 2020, developed the guidelines on the PSC (State Corporations and Public Universities) Disciplinary Appeal ...
The Public Service Commission
core   +1 more source

Local Media Ecologies

Nordicom Review, 2019
Legacy media and social media are intertwined in a complicated relationship in local media ecologies. The recent national Swedish SOM survey on media use shows that people use Facebook more than local newspapers (both paper and online) to stay up to date
Nygren Gunnar
doaj   +1 more source

Harnessing Large‐Scale Multi‐Omics Data for Risk Prediction and Deep Phenotyping of Valvular Heart Diseases in the General Population

Advanced Science, EarlyView.
Large‐scale UK Biobank analyses identify clinical and proteomic signatures for early prediction of valvular heart disease and its subtypes. Proteins add predictive value for VHD, AVS, and MVR, with outcome‐specific compact panels showing translational potential. Multi‐layer evidence highlights matrix remodeling, protease regulation, immune inflammation,
Zhihao Jiang, Yang Liu, Mingyu Song, Ning Chen, Canqing Yu, Jun Lv, Eric Yuk Fai Wan, Lu Qi, Liming Li, Dianjianyi Sun, Bang Zheng   +10 more
wiley   +1 more source

Bridging youth ‘media egocentrism’ and journalistic values: strategies for public service media

Frontiers in Communication
Public service media (PSM) in Europe continues to grapple with redefining its role in a rapidly evolving media landscape, balancing quality and accessibility while striving to engage diverse audiences—including younger and marginalized groups—in an ...
Juan Manuel Prieto-Arosa, Leen d’Haenens   +1 more
doaj   +1 more source