Results 51 to 60 of about 5,719,305 (315)

Could Fire and Rescue Services identify older people at risk of falls? [PDF]

open access: yes, 2011
Protecting or improving the efficiency and effectiveness of services while reducing costs in response to public sector funding reductions is a significant challenge for all public service organisations.
Anne H. Laybourne   +8 more
core   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Process evaluation of a programme to empower community nurse leadership

open access: yesBMC Nursing, 2021
Background The Nurses in the Lead (NitL) programme consists of a systematic approach and training to 1) empower community nurses in implementing evidence, targeted at encouraging functional activities of older adults, and 2) train community nurses in ...
Ruth G. M. Vogel   +6 more
doaj   +1 more source

An outbreak of hepatitis C virus attributed to the use of multi-dose vials at a colonoscopy clinic, Waterloo Region, Ontario

open access: yesCanada Communicable Disease Report, 2021
Background: Hepatitis C virus (HCV) transmission has been epidemiologically linked to healthcare settings, particularly out-of-hospital settings such as endoscopy clinics and hemodialysis clinics. These have been largely attributed to lapses in infection
Arianne Folkema   +7 more
doaj   +1 more source

State aid and public services in Europe: the limitations of the EC package [PDF]

open access: yes, 2005
This critique of the EC 2005 proposals on state aid and the implications for public services presents the historical and legal context, their impact on the expansion of private sector activity in the market for public services, a critical analysis of the
Hall, David
core  

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

The welfare state driving “me” and “we” medicine – a critical discourse analysis

open access: yesNew Genetics and Society, 2020
This study explored the relationship between visions of personalized medicine, for-profit companies, and state governance in the context of an ongoing discussion of “me” vs. “we” medicine.
Morten Deleuran Terkildsen   +3 more
doaj   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Individual-level characteristics and geospatial factors associated with cervical cancer screening participation in Alberta, Canada: a population-based cross-sectional study

open access: yesBMC Public Health
Background Cervical cancer is the fourth most common cancer in women worldwide. Effective primary prevention with human papillomavirus vaccination and secondary prevention with screening can prevent most cervical cancer cases.
Jessica Law   +11 more
doaj   +1 more source

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