Results 71 to 80 of about 5,734,629 (315)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Correction to: Prioritising the development of severity distributions in burden of disease studies for countries in the European region

Archives of Public Health, 2020
In the original publication of this article [1], the author pointed out the legends of Figs. 1 and 2 are not entire. The correct legends are:
Grant M. A. Wyper, Ian Grant, Eilidh Fletcher, Neil Chalmers, Gerry McCartney, Diane L. Stockton   +5 more
doaj   +1 more source

Exploring the Revenue Mix of Nonprofit Organizations -- Does it Relate to Publicness [PDF]

, 2007
Nonprofit organizations offer a wide range of goods and services and seek funding from a variety of revenue sources. Our working theory n this paper is that the sources of funding are related to the services a nonprofit provides - specifically whether ...
Amanda L. Wilsker, Dennis R. Young, Robert L. Fischer   +2 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Arm’s Length Provision of Public Services [PDF]

We analyze the economic consequences of strategic delegation of the right to decide between public or private provision of governmental service and/or the authority to negotiate and renegotiate with the chosen service provider.
Christian Schultz, Morten Bennedsen
core   +3 more sources

Improving public services through open data: public toilets [PDF]

, 2012
Bichard’s work for the TACT3 project (Bichard REF Output 3) found that UK toilet provision is not centrally collated and no national map or database of toilets exists.
Atkins WS, Bichard J, Cabinet Office, data.gov.uk, Gail Knight, Garbett A, Greed C, Hanson J, Help the Aged, Holland C, Jo-Anne Bichard, Knight G, Knight G, Lam GW, London Assembly, O'Reilly T, ONS (Office of National Statistics), Openly Local, OPSI (Office of Public Sector Information), Shadbolt N, Wyman JF   +20 more
core   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Productivity in Public Services [PDF]

This paper discusses issues arising in the measurement of productivity in public services. Compared to measuring productivity in the private sector difficulties arise because the output of public services is often un-priced and because some public ...
Helen Simpson
core  

Private equity: financial investors, public services, and employment [PDF]

, 2008
The report surveys the activity of private equity and other financial investors in the water, waste and healthcare sectors in Europe.
Hall, David
core