Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
Demand and revenue implications of an integrated public transport policy. The case of [PDF]
One of the most popular options for promoting public transport use is the provision of an integrated and high quality public transport system. This was the strategy adopted by the regional government in Madrid in 1986 and since then public transport ...
Anna Matas
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ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef +2 more
wiley +1 more source
Identification of Segments of French Urban Public Transport with a Latent Class Frontier Model [PDF]
This paper analyses technical efficiency of French urban public transport from 1995 to 2002 with unbalanced panel data. The latent class frontier model is used allowing the identification of different segments in the production frontier.
Carlos Barros, William Roy
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Exploring co-creation networks : creating balanced centricity within a public transport service [PDF]
This presentation looks at exploring co-creation networks and creating balanced centricity within a public transport ...
Alexander, Matthew, Jaakkola, Elina
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This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel +4 more
wiley +1 more source
The demand for urban transport: An application of discrete choice model for Cadiz [PDF]
The study of the demand for transport has among others applications, the valuation of travel time saving that is a very important question in cost-benefit analysis, and to adopt transport policy tools. Since McFadden developed a discrete choice model for
Candelaria Barrios Gonzalez +1 more
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Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham +7 more
wiley +1 more source
Evaluation of public transport satisfaction in the Tri-City: implications for sustainable mobility
Urbanisation, defined as the process of increasing urban population and the development of cities, is a global phenomenon with diverse directions and scenarios across different world regions, including Europe.
Barbara Pawłowska +2 more
doaj +1 more source
Not optimal, but Effective: the Multi-Mode Ticket for Reducing Urban Traffic Congestion in Medium-Sized Towns [PDF]
Stadtverkehr, Stadtverkehrspolitik, Öffentlicher Personennahverkehr, Verkehrsstau, Mittelstadt, Urban transport, Urban transport policy, Public Transport, Traffic jam, Medium-size ...
Ronnie Schöb
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