Results 111 to 120 of about 2,146,205 (297)

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

Analysis of principal trends of mobility related to location policy, car ownership, supply policy and ageing of population [PDF]

open access: yes
In transport analysis, we generally have several correlative explanatory variables when we want to explain the evolution of a factor. Therefore the quantification of the contribution of each variable in the evolution of our study object is often ...
Pascal Pochet, Patrick Bonnel
core  

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

The significance of internal integration of public transport for improving offer [PDF]

open access: yesUrbani Izziv, 2004
The article summarises some of the findings of the research Development possibilities for development of public transport and settlement in the Republic of Slovenia, which is one of the first attempts at comprehensive dealing with public transport in the
Aljaž Plevnik, Marjan Lep
doaj  

Urban Transport in France : Moving to a Sustainable Policy [PDF]

open access: yes
The organisation of urban public transport in France has some specificity in comparison to other European countries, even if problems are similar and the creation of the European Union leads progressively to an harmonisation.
Bruno Faivre D'Arcier
core  

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

BASIC CHARACTERISTICS OF PUBLIC PASSENGER TRANSPORT FROM THE TRANSPORT USER POINT OF VIEW

open access: yesPerner’s Contacts, 2010
This article deals with problems of public passenger transport from the transport user point of view. Than there are characterized properties of each mode of transport including of course also public passenger transport. Specifically there are following
Rudolf Kampf, Nina Kudláčková
doaj  

The National Transport Data Framework [PDF]

open access: yes, 2008
Report by Professor Peter Landshoff (Cambridge University) and Professor John Polak (Imperial College London) on a project for the Department for Transport.
Landshoff, Peter Vincent, Polak, John
core  

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

Ownership, Contractual Practices and Technical Efficiency: The Case of Urban Public Transport in France [PDF]

open access: yes
This paper investigates the impact of ownership structure and contractual choices on technical efficiency in the French urban public transport sector. The central proposition, which relies on classical contract theory arguments, is that ownership regime ...
Anne Yvrande-Billon, William Roy
core  

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