Results 41 to 50 of about 503,934 (294)

Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy

open access: yesFEBS Letters, EarlyView.
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile   +8 more
wiley   +1 more source

Crime on Public Transport [PDF]

open access: yes, 2014
This entry examines how crime concentrates and is potentially specialized within and around the public transport system. It begins by defining public transport for the purposes of this discussion and outlines why this is an area of importance. It also discusses some of the reasons why there is a paucity of evidence into crime on public transport and ...
openaire   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Identification of Sleeper Support Conditions Using Mechanical Model Supported Data-Driven Approach

open access: yesSensors, 2021
The ballasted track superstructure is characterized by a relative quick deterioration of track geometry due to ballast settlements and the accumulation of sleeper voids.
Mykola Sysyn   +3 more
doaj   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

Environmentally Friendly Public Transport

open access: yesTransactions on Transport Sciences, 2014
The article “Environmentally Friendly Public Transport” deals with the impact of public transport on the environment by selected types of vehicles.
Pejšová M.
doaj   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

Sustainable Mobility In the city Of Bratislava - Tram Priority

open access: yesCommunications, 2013
United Nations Development Programme (UNDP), acting as an implementing agency of the Global Environment Facility (GEF) implemented the project "Sustainable Mobility in the City of Bratislava".
Jan Fischer
doaj   +1 more source

A review of public transport economics

open access: yesEconomics of Transportation, 2020
Public transport provision requires substantial organisational efforts, careful planning, in some cases contributions from the public purse, and coordination between millions of passengers and staff members in large systems. Efficient resource allocation is critical in its daily operation, and therefore public transport has been among the most popular ...
Daniel Hörcher   +2 more
openaire   +5 more sources

Profiling public transport users through perceptions about public transport providers and satisfaction with the public transport service [PDF]

open access: yesPublic Transport, 2016
Priority has been given to increasing public transport use in the mobility programmes of developed countries as part of a global strategy to manage traffic congestion and air pollution in urban areas. Understanding citizens’ travelling behaviour, their perceptions and satisfaction after experiencing public transport services is crucial to the ...
Vicente, Paula, Reis, Elizabeth
openaire   +4 more sources

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