Results 51 to 60 of about 2,146,205 (297)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

PUBLIC TRANSPORT AND INNOVATION

International Journal of Advanced Studies, 2019
The effective functioning of the transport system of the region creates the necessary conditions for the development of the economy and the social sphere.
Nina Demidovna Berman, Alexander Mikhailovich Belov   +1 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Orientation of Blind and Visually Impaired People - Case Study [PDF]

, 2019
This paper is focused on evaluation of barrierfree accessibility of the significant regional transfer junction in Ostrava made up of the Ostrava-Svinov railway station and upper and lower stops of the urban mass transportation. The outcome is focused
Bílková, Alžběta, Kocurová, Petra, Zdařilová, Renata   +2 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

The Competitiveness of Public Transport [PDF]

Journal of Competitiveness, 2017
Examining the competitiveness of public transport plays an important role because through public transport, the transport of passengers to schools, public healthcare establishments and work is ensured. In addition, transportation for vulnerable groups of
Poliak Milos, Poliakova Adela, Mrnikova Michaela, Simurková Patricia, Jaskiewicz Marek, Jurecki Rafał   +5 more
doaj   +1 more source

Passengers preference and satisfaction of public transport in Malaysia [PDF]

, 2012
Nowadays, Malaysia facing with an explosive growth in vehicle ownership and utilization, which led to traffic congestion and pollution. In this situation, government policy encourages people to use public transportation.
Ambak, Kamarudin, Hafezi, Mohammad Hesam, Ismail, Rozmi, Mohd Nor, Rahim   +3 more
core  

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Regional public transport integration in Lithuania

Mokslas: Lietuvos Ateitis
Regional public transport organization helps to avoid additional route coordination, public transport service should not be limited to the boundaries of municipalities, which is currently regulated by the Law on Local Self-Government of the Republic of ...
Andrius Samuilovas, Rasa Ušpalytė-Vitkūnienė   +1 more
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source