Results 61 to 70 of about 2,146,205 (297)

Towards sustainable transport: wireless detection of passenger trips on public transport buses

open access: yes, 2008
An important problem in creating efficient public transport is obtaining data about the set of trips that passengers make, usually referred to as an Origin/Destination (OD) matrix.
Camacho, Tiago   +2 more
core   +2 more sources

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Project FATIMA Final Report: Part 1. [PDF]

open access: yes, 1999
EXECUTIVE SUMMARY This Final Report covers the results of the EU-funded research project FATIMA (Financial Assistance for Transport Integration in Metropolitan Areas) which had the following objectives: (i) to identify the benefits to the private
May, A.D.   +3 more
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Accessibility for All: The Australian Experience [PDF]

open access: yes, 2000
development of National Standards under the Disability Discrimination Act of 1992 (DDA). The Standards will guide the implementation of an accessible public transport system in Australia.
Corcoran, Maurice
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

FLEXIBLE PUBLIC TRANSPORT SERVICE – SOLUTION FOR LOW PUBLIC TRANSPORT DEMAND AREAS

open access: yesPerner’s Contacts, 2006
This paper deals with problematic of implementation of flexible public transport service in low demand areas. In spite of many advantage, it is not such of type of public transport service implemented, even if the real reasons in operational and ...
Marián Gogola
doaj  

Generation of the transport service offer with application to timetable planning considering constraints due to maintenance work [PDF]

open access: yes, 2019
Line planning is an important step in strategic timetable planning in public transport. In this step the transport offer for the customer is generated by the public transport operator, whereby the resulting costs for the operator should be as deep as ...
Bütikofer, Stephan   +3 more
core   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

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