Results 81 to 90 of about 13,272,006 (249)
The paper deals with the question of how suspension of the subsidies for public transport operations in the Netherlands would affect the public transport system.
Kees van Goeverden, Paul Peeters
doaj +1 more source
MITF maintains genome stability in nonmelanocyte lineages
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Financing public transport: Case studies of international and Australian cities [PDF]
While the Gold Coast has been successful in negotiating $1 billion in joint funds to build its light rail system and to improve travel between its urban activity centres, the community of the Newcastle region is currently trying to prevent the closure of
Wang, W
core
Public transport plays an increasingly important role in satisfying the transport needs. Travellers’ requirements regarding the quality of services are increasing.
Piotr Gołębiowski +2 more
doaj
Spatial biology in cancer epigenetics
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Cities in the developing world are growing both geographically and demographically. Thisgrowth has increased pressure on services, including the public transport systems used bythe majority of people.
Tatenda Mbara +2 more
doaj +1 more source
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Conveying geospatial public transport information on the world-wide web: a review of the United Kingdom sources [PDF]
The Geospatial Public Transport Information available for the United Kingdom on the World-Wide Web is evaluated. Searches for relevant websites were made at different geographical scales; the breadth of content covered and level of technology used was ...
Forrest, D., Scrimgeour, R.
core +1 more source
THE IMPORTANCE OF PUNCTUALITY IN PARTICULAR SEGMENTS OF PUBLIC TRANSPORT USERS: A CASE STUDY FROM GDYNIA (POLAND) [PDF]
Increasing the share of trips using public transport is a long-term activity that necessitates continuous improvement of the offer. What is crucial here is not only the tangible sphere, measured by objective indicators of punctuality, but also the ...
Marcin WOŁEK +3 more
doaj +1 more source
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source

