Results 81 to 90 of about 13,272,006 (249)

Financially independent public transport; its impacts on the public transport system in the Netherlands

open access: yesEuropean Journal of Transport and Infrastructure Research, 2005
The paper deals with the question of how suspension of the subsidies for public transport operations in the Netherlands would affect the public transport system.
Kees van Goeverden, Paul Peeters
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Financing public transport: Case studies of international and Australian cities [PDF]

open access: yes, 2013
While the Gold Coast has been successful in negotiating $1 billion in joint funds to build its light rail system and to improve travel between its urban activity centres, the community of the Newcastle region is currently trying to prevent the closure of
Wang, W
core  

The Selected Problems of Public Transport Organization Using Mathematical Tools on the Example of Poland

open access: yesTehnički Glasnik, 2020
Public transport plays an increasingly important role in satisfying the transport needs. Travellers’ requirements regarding the quality of services are increasing.
Piotr Gołębiowski   +2 more
doaj  

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Multi-stakeholder dialogue on formal and informal forms of public transport in Harare, Zimbabwe: Convergence or divergence perspective

open access: yesJournal of Transport and Supply Chain Management, 2014
Cities in the developing world are growing both geographically and demographically. Thisgrowth has increased pressure on services, including the public transport systems used bythe majority of people.
Tatenda Mbara   +2 more
doaj   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

Conveying geospatial public transport information on the world-wide web: a review of the United Kingdom sources [PDF]

open access: yes, 2008
The Geospatial Public Transport Information available for the United Kingdom on the World-Wide Web is evaluated. Searches for relevant websites were made at different geographical scales; the breadth of content covered and level of technology used was ...
Forrest, D., Scrimgeour, R.
core   +1 more source

THE IMPORTANCE OF PUNCTUALITY IN PARTICULAR SEGMENTS OF PUBLIC TRANSPORT USERS: A CASE STUDY FROM GDYNIA (POLAND) [PDF]

open access: yesScientific Journal of Silesian University of Technology. Series Transport
Increasing the share of trips using public transport is a long-term activity that necessitates continuous improvement of the offer. What is crucial here is not only the tangible sphere, measured by objective indicators of punctuality, but also the ...
Marcin WOŁEK   +3 more
doaj   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy