Results 71 to 80 of about 636,686 (304)
Financing public transport: Case studies of international and Australian cities [PDF]
, 2013 While the Gold Coast has been successful in negotiating $1 billion in joint funds to build its light rail system and to improve travel between its urban activity centres, the community of the Newcastle region is currently trying to prevent the closure of
Wang, W
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Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Changing the climate of public transport : a design research initiative
, 2007 The Public Transport Design Research Initiative, developed by Monash University’s Faculty of Art & Design and the Institute of Transport Studies in 2005, aims to develop original and innovative design concepts and approaches to address the challenges ...
Coxon, Selby +2 more
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Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
FLEXIBLE PUBLIC TRANSPORT SERVICE – SOLUTION FOR LOW PUBLIC TRANSPORT DEMAND AREAS
Perner’s Contacts, 2006 This paper deals with problematic of implementation of flexible public transport service in low demand areas. In spite of many advantage, it is not such of type of public transport service implemented, even if the real reasons in operational and ...
Marián Gogola
doaj
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
European Journal of Transport and Infrastructure Research, 2005 The paper deals with the question of how suspension of the subsidies for public transport operations in the Netherlands would affect the public transport system.
Kees van Goeverden, Paul Peeters
doaj +1 more source
Replanning public transport services in the case of budget reductions
, 2014 The planning of an efficient and effective public transport system is a key element in managing modern mobility both in densely populated urban areas and in peripheral and/or rural areas where the population densities are considerably lower.
D'ACIERNO, LUCA
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Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source