Results 71 to 80 of about 229,729 (256)

The roadmap and strategy for prioritizing the development of public transport in China

open access: yesMultimodal Transportation
With the acceleration of urbanization and continuous population growth in China, transportation issues in central cities, especially large and mega-cities, have become increasingly prominent.
Jing Wang   +5 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

ROUTE OPTIMIZATION OF URBAN PUBLIC TRANSPORTATION

open access: yesDyna, 2013
Este artículo muestra el proceso de optimización de rutas de transporte público urbano basado en las técnicas de investigación de operaciones. Éste muestra en el contorno del desarrollo e importancia de la planifi cación del transporte público colectivo ...
PATRICIA JARAMILLO-ÁLVAREZ   +2 more
doaj  

From Attitude to Action: Exploring Factors Influencing Switching Behavior of Public Transport Users

open access: yesJournal of Consumer Sciences
Background:  The number of vehicles in Denpasar has increased, while the public still hesitates to use public transportation, contributing to traffic congestion in Denpasar.
Ni Putu Cempaka Dharmadewi Atmaja   +2 more
doaj   +1 more source

Association Between Public Transportation Use and Loneliness Among Urban Elderly People Who Stop Driving

open access: yesGerontology and Geriatric Medicine, 2019
Aim: To examine the association between public transportation use and loneliness in urban elderly who stop driving. Methods: In this cross-sectional study, we assessed 31 community-dwelling older adults who had stopped driving.
Naoka Matsuda PT, MS   +10 more
doaj   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

open access: yesMolecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant   +7 more
wiley   +1 more source

Travel Satisfaction of Persons with Disabilities in Metropolitan Indonesia: A Case of Jakarta

open access: yesIndonesian Journal of Disability Studies
Many studies have been conducted on travel satisfaction with public transportation in various countries. However, no studies have reached inclusive groups such as persons with disabilities, although most of them depend on public transportation ...
Husnul Fitri, Diah Rini Lesmawati
doaj   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

open access: yesFEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia   +3 more
wiley   +1 more source

Organic Transportation Networks: Human-Oriented Renewal of Modern Megapolises

open access: yesARCHive-SR, 2019
Studies related to the growth of the transportation networks from the second half of the 20th century have constantly been focused on the topological complexity of motorized & public transportation network (internal geometry & dynamics, occupied space ...
Oleksandr Galychyn   +2 more
doaj   +1 more source

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