Results 111 to 120 of about 11,862,425 (370)
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Front Cover, Publication Information [PDF]
Front Cover, Publication Information, Table of ...
core +1 more source
Public funding, public knowledge, publication
The argument that publicly funded research should be publicly available is a valid one, but it cannot be the most important one in the discussion as to whether research should be freely accessible. The overriding argument is that freely accessible research optimises the scientific process as well as its 'translation' into societal benefits. Free access,
openaire +2 more sources
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Front Cover and Publication Information [PDF]
Front cover and publication information for this issue, including the table of ...
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Moringa oleifera: A Bibliometric Analysis of International Publications during 1935-2019
BM Gupta, KK Mueen Ahmed
openalex +1 more source
https://www.researchgate.net/publication/329529188_Comparative_Performance_Prediction_of_Historical_Thames_A_Rater_Class_Designs [PDF]
The Thames A-Rater fleet is a unique class both in appearance and in its combination of historic and modern technologies. With high aspect ratio, carbon fibre rigs fitted onto wooden hulls, many of which have survived two World Wars, the class is a ...
Souppez, Jean-Baptiste, Thomas, Joseph
core

