Results 121 to 130 of about 11,862,425 (370)
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Managing for change: August 9, 1991 v. 2, no. 5 [PDF]
, 1991 Bi-weekly newsletter of University Hospital's Change Project, provided to managers at the ...
Abercrombie, J. Scott, Jr. +1 more
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Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Frontiers in NanotechnologyNanoelectronic Drug Delivery Systems (NEDDS) represent a transformative convergence of nanotechnology, electronic engineering, and precision medicine.
Val Hyginus Udoka Eze +8 more
doaj +1 more source
Managing for change: September 20, 1991 v. 2, no. 6 [PDF]
, 1991 Bi-weekly newsletter of University Hospital's Change Project, provided to managers at the ...
Abercrombie, J. Scott, Jr. +1 more
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In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
The MIQE guidelines: minimum information for publication of quantitative real-time PCR experiments.
Clinical Chemistry, 2009 S. Bustin +11 more
semanticscholar +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Special connections: June 1, 1993 [PDF]
, 1993 Time-sensitive news update to monthly University Hospital ...
Office of Publication Services, Boston University Medical Center
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