Results 61 to 70 of about 10,706,018 (302)

Prognosis of Long‐Term Continuous Renal Replacement Therapy and the Impact of Combined Continuous Intravenous Sodium Infusion Therapy

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Patients requiring long‐term continuous renal replacement therapy (CRRT) generally have poor prognoses. This study evaluated whether adding continuous intravenous sodium infusion (cIVNa) is associated with improved hemodynamics and outcomes in patients undergoing long‐term CRRT for ≥ 7 days.
Akinori Yamaguchi   +6 more
wiley   +1 more source

Circular RNA therapeutics: a new class of long-acting RNA medicines for oncology, immunology, and rare diseases

open access: yesFrontiers in Immunology
Circular RNAs (circRNAs) have progressed from being viewed as splicing by-products to emerging therapeutic constructs with a distinct pharmacology. Their covalently closed topology can increase RNA stability, prolong intracellular persistence, and under ...
Okechukwu Paul-Chima Ugwu   +4 more
doaj   +1 more source

Publications [PDF]

open access: yesHealth Policy and Planning, 2000
The World Health Organization (WHO) has recently published a booklet of Guidelines for the Regulatory Assessment of Medicinal Products for use in Self-Medication. The guidelines' purpose is to suggest criteria and methods which drug regulatory authorities can use in determining the suitability of medicinal products for self-medication.
openaire   +2 more sources

Special connections: September 12, 1991 [PDF]

open access: yes, 1991
Time-sensitive news update to monthly University Hospital ...
Office of Publication Services, Boston University Medical Center
core  

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Impact of students’ self-regulation and mindfulness on academic self-efficacy; the mediation effect of mental well-being

open access: yesCogent Education
This study explored how academic self-efficacy was affected by self-regulation, mindfulness and their indirect impacts through mental well-being among higher education students in the Maldives.
Mariyam Shareefa   +4 more
doaj   +1 more source

Special connections: April 9, 1992 [PDF]

open access: yes, 1992
Time-sensitive news update to monthly University Hospital ...
Office of Publication Services, Boston University Medical Center
core  

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Special connections: January 14, 1991 [PDF]

open access: yes, 1991
Time-sensitive news update to monthly University Hospital ...
Office of Publication Services, Boston University Medical Center
core  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

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