Results 111 to 120 of about 4,317,100 (298)

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Bibliometrics of Bibliometrics: A Research Topic in the Mirror of Bibliometric Indicators [PDF]

open access: yes
This exploratory study tries to get insights on one way of exteriorizing the publication activity of bibliometricians and how such activity is taken into consideration within the scientific community. As we thought in advance, the evidence shows that the
Víctor Rodríguez
core  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Contemporary Russian linguists: bibliometric analysis of publication activity and citation rate

open access: yesRussian Language Studies, 2019
Objective assessment of the results of scientific work, including the possibility of using the bibliometric (statistical, mathematical) assessment of publication activity, citation and, ultimately, the prestige of scholars, has been the subject of wide ...
Eduard Vladimirovich Budaev   +1 more
doaj   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

SCIENTOMETRIC APPROACH IN DETERMINING THE ROLE OF SCIENCE IN SOCIOECONOMIC DEVELOPMENT OF SOCIETY

open access: yesJournal of Social Sciences
This study investigates the relationship between scientific advancement and socioeconomic progress using a scientometric methodology. The research examines publication activity and the Science Development Index (SDI) in different countries, utilizing ...
DIKUSAR, Alexandr, CUJBA, Rodica
doaj   +1 more source

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