Results 121 to 130 of about 1,664,402 (304)

α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates

open access: yesFEBS Letters, EarlyView.
Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino   +2 more
wiley   +1 more source

Taste Heterogeneity and Substitution Patterns in Models of the Simultaneous Choice of Activity Timing and Duration [PDF]

open access: yes
The recent growth of interest in activity-based methods has focused particular attention on travellers’ decision making regarding the timing and duration of their participation in activities.
Olu Ashiru   +3 more
core  

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Physical activity among adolescents and barriers to delivering physical education in Cornwall and Lancashire, UK: A qualitative study of heads of PE and heads of schools

open access: yes, 2008
BACKGROUND: Recent initiatives have been introduced by the UK government into secondary schools to increase pupils' access to physical activity (PA).
Boyle Spencer   +14 more
core   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Photograph - Pavement art - Student Union activity

open access: yes, 2019
This record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete.
University Of Melbourne. Media And Publication Services Office
core  

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

CERAPP- Collaborative Estrogen Receptor Activity Prediction Project: Data Associated with Publication

open access: yes, 2018
Data associated with publication on CERAPP- Collaborative Estrogen Receptor Activity Prediction Project.
EPA's National Center for Computational Toxicology (5039467)
core   +1 more source

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