Results 131 to 140 of about 1,664,402 (304)

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

DEVELOPMENT OF AN INFORMATION SYSTEM FOR MANAGING SCIENTIFIC ACHIEVEMENTS AND CAREER GROWTH OF ACADEMIC STAFF IN HIGHER EDUCATION INSTITUTIONS

open access: yesАвтоматизация технологических и бизнес-процессов
Modern trends in the digitalization of education and science require the implementation of efficient information systems for managing scientific achievements and career development of academic staff in higher education institutions (HEIs).
D. Semonkin, O. Sakaliuk, P. Lomovtsev
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Physical Activity... A healthy habit for Life!

open access: yes, 2013
Discusses the benefits of physical activity, some common guidelines and an activity ...
Jones, Debra S.
core  

Scientific publication activity during COVID-19 shutdown. [PDF]

open access: yesClin Res Cardiol, 2020
Böhm M, Ewen S, Schweitzer A, Katus H.
europepmc   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Building Healthy Meals Together

open access: yes, 2014
This publication helps teach you and your kids the building blocks of a balanced meal and a healthy life with food and physical ...
Farris, Alisha, Serrano, Elena L.
core  

The university library activity as a factor of publication activity growth of the institution

open access: yesБиблиосфера, 2015
The article shows actuality of a new function of a modern university library supporting publication activity of the institution. The ways of the function realization are described and illustrated by experiences of domestic and foreign libraries.
T. V. Eremenko
doaj  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Physical Activity Guidelines for Children & Adults

open access: yes, 2018
Lists benefits of physical activity, and provides exercise guidelines for adults and children, including amount per week for aerobic activity, strength training, and ...
Harden, Samantha M.
core  

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