Results 111 to 120 of about 1,284,186 (296)
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Fabio Targhetta, Serenant et illuminant. I cento anni della SEI
Strenae, 2012 Michel Manson
doaj +1 more source
Volume 11 of the History of Russia: A Political Economist’s Opinion
Вестник Северного (Арктического) федерального университета: Серия «Гуманитарные и социальные науки»The article provides a brief description of volume 11 of the 20-volume History of Russia from the perspective of a political economist. The review highlights the main advantages of this publication and its severe disadvantages related to ignoring both ...
Vasily Yu. Galin
doaj +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Mariella Colin (dir.), Les catéchismes et les littératures chrétiennes pour l’enfance en Europe
Strenae, 2015 Frédéric Gugelot
doaj +1 more source
QUANTIFYING THE HETEROGENITY OF PUBLICATION CULTURES IN ECONOMIC, BUSINESS, AND FINANCIAL HISTORY
Essays in Economic and Business History, 2016 Researchers working in the interdisciplinary field of ‘economic, business and financial history’ come from at least two different disciplinary backgrounds, namely history and economics. These two backgrounds may lead to differences in research practices,
Eline Poelmans, Sandra Rousseau
doaj
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Authors of the latest books published by the Presbyterian Board of Publication
, 1900 This item is from the Manly Family papers. The collection includes the papers of Basil Manly, president of the University of Alabama, 1837-1855, and a founder of Furman University, which reflect the history of the period as well as his life as theologian
Presbyterian Board of Publication
core
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source