Results 81 to 90 of about 1,284,186 (296)
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Review article of the publication: Oral history spod Triglava (Oral History Education. Dialogue with the Past, red. D. Trškan, Ljubljana 2016, ss. 235)
Michał Kierzkowski
doaj +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Review of the book: Badr al-Din Muhammad b. Muhammad Kaysuni-zadeh Nidai-efendi (Remmal-khoja). The History of Khan Sahib Giray (Moscow, 2023) [PDF]
The review provides a brief overview of the publication of “The History of Khan Sahib Giray”, carried out in 2023 by I.V. Zaitsev and R.R. Abduzhemilev, which serves the urgent task of studying and publishing sources on the history of the Crimean Khanate
Tatiana Anikeeva
doaj +1 more source
A History of Women in 100 Objects
The history of the world has been told in objects. But what about the objects that tell the history of women? What are the items that symbolise the journey of women from second-class citizens with no legal rights, no vote and no official status to the ...
Andrews, Maggie, Lomas, J.
core
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
From the history of collection, publication, comprehension of abaza fairy-tale prose
The article recreates the history of the collections, writings and publications of Abaza fairy tales from 1929 to the present time. In this regard, the activities of A.N. Genko, T.Z. Tabulov, K.V. Lomtatidze, V.B. Tugov, V.N.
Lilya A. Borokova
doaj +1 more source
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source

