Results 121 to 130 of about 8,221,589 (337)

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias   +12 more
wiley   +1 more source

Research on automatic generation of civil aircraft consumable product manual based on S1000D specification

open access: yesHangkong gongcheng jinzhan
At present,consumable product manual(CPM)is written manually,which wastes manpower and is easy to produce inconsistent manual contents. To solve this problem,a method of automatic generation of homologous manual based on S1000D standard is studied.
LI Mengxia, YANG Yang
doaj   +1 more source

Text and Graph Based Approach for Analyzing Patterns of Research Collaboration: An analysis of the TrueImpactDataset [PDF]

open access: yes, 2018
Patterns of scientific collaboration and their effect on scientific production have been the subject of many studies. In this paper, we analyze the nature of ties between co-authors and study collaboration patterns in science from the perspective of ...
Herrmannova, Drahomira   +4 more
core  

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Research Collaboration Analysis Using Text and Graph Features [PDF]

open access: yes, 2018
Patterns of scientific collaboration and their effect on scientific production have been the subject of many studies. In this paper we analyze the nature of ties between co-authors and study collaboration patterns in science from the perspective of ...
Herrmannova, Drahomira   +4 more
core  

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner   +6 more
wiley   +1 more source

Department Publications 2009 [PDF]

open access: yes
This publication is a list of books, chapters, journal articles, staff papers, The Food Industry Center publications, International Science & Technology Practice & Policy Center papers, miscellaneous monographs, Center for Farm Financial Management ...
Kill, Sharon, Letnes, Louise
core   +1 more source

EGFR‐STAT3 activation provides a therapeutic rationale for targeting aggressive ETV1‐positive prostate cancer

open access: yesMolecular Oncology, EarlyView.
Cotargeting EGFR and STAT3 with Erlotinib and TTI‐101 impairs both 2D and 3D growth of ETV1‐overexpressing prostate cancer cells by disrupting a self‐sustaining ETV1–EGFR positive feedback loop that promotes EGFR and STAT3 expression and phosphorylation (activation).
Elsa Gomes Paiva   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy