Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Design and analysis of an efficient distributed event notification service [PDF]
, 2004 Event Notification Services (ENS) use the publish/subscribe paradigm to continuously inform subscribers about events they are interested in. Subscribers define their interest in so-called profiles.
Bittner, Sven, Hinze, Annika
core
Specifying and detecting composite events in content-based publish/subscribe systems
, 2002 Content-based publish/subscribe systems mediate between publishers of information and subscribers who sign up to receive information, by routing messages across the network from their source of publication to the point of subscription using the message ...
Courtenage, S., S. Courtenage
core +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Automatic hyperlink creation using p2p and publish/subscribe
, 2005 . The World-Wide Web allows users to quickly and easily publish information in the form of web pages. Pages are linked to other pages already on the web using a hyperlink inserted into a web page by the page’s author that contains the URL address of ...
Steven Williams +3 more
core +1 more source
Security-Enhanced Decentralized Content Sharing in Publish/Subscribe System
IEEE AccessWe consider a content dissemination model, where the contents disseminated from a content source on a regular or event-driven basis are shared among the group members, without directly contacting the content source.
Wang-Seok Park +2 more
doaj +1 more source
Publish/Subscribe Method for Real-Time Data Processing in Massive IoT Leveraging Blockchain for Secured Storage. [PDF]
Sensors (Basel), 2023 Ataei M +4 more
europepmc +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
AHS Model: Efficient Topological Operators for a Sensor Web Publish/Subscribe System
ISPRS International Journal of Geo-Information, 2017 The Worldwide Sensor Web has been applied for monitoring the physical world with spatial and temporal scales that were impossible in the past. With the development of sensor technologies and interoperable open standards, sensor webs generate tremendous ...
Chih-Yuan Huang, Steve H. L. Liang
doaj +1 more source
Flexible and Efficient Security Framework for Many-to-Many Communication in a Publish/Subscribe Architecture. [PDF]
Sensors (Basel), 2022 Van Glabbeek R +4 more
europepmc +1 more source