Results 81 to 90 of about 1,420,968 (272)
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
PLoS ONE, 2017 ObjectivesTo systematically review AKI outcome prediction models and their external validation studies, to describe the discrepancy of reported accuracy between the results of internal and external validations, and to identify variables frequently ...
Tetsu Ohnuma, Shigehiko Uchino
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Dyna, 2013 I have the pleasure to present the Volume 80 (180) - Advances in Systems and Computing as a special edition published in the DYNA Journal. In this Volume are published eleven articles which were reviewed by external peers with a worldwide renowned ...
Jovani Alberto Jiménez Builes
doaj
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
, 2021 We point out that the recently published Publisher’s Note concerning two retractions in Journal of Radiological Protection and the retraction notices contain various incorrect statements, misrepresentations of facts and omission of important events.
Yoh Tanimoto +5 more
openaire +3 more sources
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Breast Cancer: Learning about Radiation Therapy
EDIS, 2010 FCS8835, a 3-page fact sheet by Martha C. Monroe and Barbara F. Shea, provides a basic orientation to external radiation therapy for the treatment of breast cancer. Published by the UF Department of Family Youth and Community Sciences, February 2010.
Martha C. Monroe, Barbara F. Shea
doaj +1 more source