Publisher Correction: Enhanced unbiased sampling of protein dynamics using evolutionary coupling information [PDF]
Zahra Shamsi +2 more
openalex +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Sampen HJI, Sharrocks AD, Lin X, et al. Open Access Rheumatol. 2009;1:151–161. We, the Editor and Publisher of the journal Open Access Rheumatology: Research and Reviews are issuing an expression of concern for the published article.
Sampen HJI +7 more
doaj
Information rules - a strategic guide to the network economy
C. Shapiro, H. Varian
semanticscholar +1 more source
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
Book review: Language and Representation in Information Retrieval by D.C. Blair. Elsevier Science Publishers 1990 [PDF]
Peter Bruza
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The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Positive, enthusiastic: Mitchell, Anne M, and Surratt, Brian ECataloging and organizing digital resources: a how-to-do-it manual for librariansHow-to-do-it manuals for librarians, 139. New York: Neal-Schuman Publishers, 2005. 209p US$75.00 soft ISBN 1555705219 (available from DA Information Services) [PDF]
Marie‐Laure Bouchet
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Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source

