This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini+10 more
wiley +1 more source
Book Review Society and the object. Views from the identity, design and information / Reseña La sociedad y el objeto. Miradas desde la identidad, diseño e información [PDF]
Book Review: Mercedes Mercado; Álvaro Ríos; Liliana Sosa; and Gerardo Vázquez (2012) Identity, design, information. Publisher: University of Nuevo León, Monterrey (Mexico). Pages: 195. ISBN: 978-607-27-0016-1.
Jesús Manuel Fitch Osuna
doaj
Quality source for cancer information:The Medical Library Association Guide to Cancer Information: Authoritative, Patient-Friendly Print and Electronic Resources.By Ruth M. Volk. Medical Library Association Guides. New York: Neal-Schuman Publishers, 2007. 331 pp. US$85.00 soft cover ISBN 9781555705855 (available from DA Information Services) [PDF]
R Robert Cullen
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Information of field experiments in the published references.
Information of field experiments in the published references.
openaire +2 more sources
The roles and applications of extracellular vesicles in cancer
Extracellular vesicles (EVs) are minute versions of cells limited by a lipid bilayer containing cytoplasm from the cell that releases them, but without a nucleus and thus unable to self‐reproduce. EVs contain multiple molecules (proteins, lipids, glycans, and nucleic acids) they can induce complex responses in cells.
Clotilde Théry, Daniel Louvard
wiley +1 more source
Libraries for families:The Family-Centered Library Handbook.By Sandra Feinberget al.New York: Neal-Schuman Publishers, 2007. 324 pp. US$65.00 soft cover ISBN 13: 9781555705411 (available from DA Information Services) [PDF]
Lyn Linning
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TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair+17 more
wiley +1 more source
Practical approach to professional indemnity–highly recommended:Professional liability issues for librarians and information professionals. By Paul D. Healey. The Legal Advisor for Librarians, Educators and Information Professionals. New York: Neal–Schuman Publishers, 2008. 235 pp. price not reported soft cover ISBN 9781555706098 [PDF]
Lois Robertson
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There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes+20 more
wiley +1 more source