Results 131 to 140 of about 2,303,005 (336)
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
IntroductionWith the increasing number of children’s publications that integrate new media technologies in the global publishing community, understanding the adoption and use of these publications from a child’s perspective is of great significance for ...
Jiayong Cui +7 more
doaj +1 more source
Vascular access simplified. A. H. Davies and C. P. Gibbons (eds). 149 × 210 mm. Pp. 196. Illustrated. 2003. tfm Publishing Ltd: Shrewbury [PDF]
Zahid Raza
openalex +1 more source
Publisher’s announcement [PDF]
openaire +2 more sources
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source
IntroductionWith the acceleration of global urbanization, the development of female-friendly cities has become a key objective in urban planning. This study investigates strategies for optimizing residential community facilities in Yangpu District ...
Zhiguo Fang, Jiachen Yao, Jianing Shi
doaj +1 more source

