Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona +4 more
wiley +1 more source
Book review: a tale of two books: digital transformations are creeping across the face of academic life [PDF]
In response to Patrick Dunleavy’s posts on the future of e-publishing in academia, David Gauntlett writes on his experiences of publishing ebooks, and how Kindle self-publishing could be an approach which gets books to readers at a far more affordable ...
Gauntlett, David
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The preparation and characterisation of monomeric and linked metal carbonyl clusters containing the closo-Si2Co4 pseudo-octahedral core [PDF]
PhSiH3 reacts with [Co₄(CO)₁₂] at 50 °C in hydrocarbon solvents to give [(µ₄-SiPh)₂Co₄(CO)₁₁], 2c, shown by an X-ray crystal structure determination to have a pseudo-octahedral Si₂Co₄ core. Substituted aryl-silanes behaved similarly.
Evans, Cameron +7 more
core +2 more sources
Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura +8 more
wiley +1 more source
Women academics publish less than men. Or do they…? [PDF]
Publishing can sometimes be seen as acting as the fuel behind the academic world. Yet, across social sciences, woman are not publishing their share of research papers.
Schucan-Bird, Karen
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BRIEF GUIDELINES FOR DESCRIPTION OF THE DIAGNOSTIC STUDY RESULTS
We bring to the attention of the authors brief guidelines for preparation of manuscripts containing description of the results of diagnostic studies. More detailed explanations are given in the corresponding template (http://vsp.spr-journal.ru/jour/about/
Ruslan T. Saygitov +1 more
doaj +1 more source
Protein kinase FAM20C—when subcellular localization matters
FAM20C is a Golgi‐resident kinase that phosphorylates proteins along the entire secretory pathway. The presence of potential FAM20C substrates in the cytoplasm or nucleus raises the question of how the kinase and its substrates encounter each other. Protein kinases achieve signaling specificity through consensus sequence recognition and subcellular ...
Francesca Noventa, Mauro Salvi
wiley +1 more source
Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley +1 more source
Book review: Publishing journal articles [PDF]
In this accessible and informative book, Lucinda Becker and Pam Denicolo seek to introduce the best practical strategies available to help academics maximise the chance of success in getting work published. Offering advice on topics including coping with
Wheeldon, Johannes
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Microstructural evolution in materials during thermal processing [PDF]
Copyright © 2012 Joseph K. L. Lai et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly ...
Chen, Z, Lai, JKL, Lo, KH, Ralph, B
core +2 more sources

