Results 81 to 90 of about 1,395,322 (291)
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Critical examination of the IEET measurement instrument for the assessment of textbook quality
Ekonomski Vjesnik, 2018 As is the case in other sectors of the creative industry, the publishing industry also evaluates its projects finalized in the form of products and services in the market of creative contents.
Ivana Ljevak Lebeda +2 more
doaj
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
WHY DO RESEARCHERS COLLABORATE WITH INDUSTRY? AN ANALYSIS OF THE WINE SECTOR IN CHILE, SOUTH AFRICA AND ITALY [PDF]
This paper explores the determinants of the linkages between industry and research organizations – including universities. We present new evidence on three wine producing areas – Piedmont, a region of Italy, Chile, South Africa - that have successfully ...
Andrea Morrison +3 more
core
A Benchmark Environment Motivated by Industrial Control Problems
, 2018 In the research area of reinforcement learning (RL), frequently novel and promising methods are developed and introduced to the RL community. However, although many researchers are keen to apply their methods on real-world problems, implementing such ...
Depeweg, Stefan +6 more
core +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
The Changing Medical Publishing Industry: Economics, Expansion, and Equity. [PDF]
J Gen Intern Med, 2023 Booth CM, Ross JS, Detsky AS.
europepmc +1 more source
Independent Publishers and Transition to Nonprofit: Distress Call or Mission-Based Evolution? [PDF]
, 2015 It has been widely reported in recent years that a few independent publishing houses, which were formed as for-profit organizations, have adopted nonprofit status.
Lobnitz, Meagan
core +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
"COVID-19 and its Impact on GSJ & the Publishing Industry". [PDF]
Global Spine J, 2022 Wang JC, Wiechert K, Chapman JR.
europepmc +1 more source