Puerarin relives inflammation, bone destruction and facilitates osteogenic differentiation in periodontitis by enhancing mitochondrial autophagy via activating mitochondrial Mitofusin 2 [PDF]
Purpose Puerarin (Pue) has recently been reported to have therapeutic effects on periodontitis (PD). However, there is insufficient evidence, and the mechanism involved has not yet been revealed.
Yulan Xiang +8 more
doaj +2 more sources
Global-scale prevalence of low nutrient use efficiency across major crops [PDF]
Enhancing nitrogen (N) and phosphorus (P) use efficiency (NUE and PUE) is essential for advancing sustainable agriculture and reducing dependency on non-renewable fertilizers.
Ji Liu +18 more
doaj +2 more sources
Evaluation of the antioxidant activity of the puerarin - β - lactoglobulin complex in vitro and in vivo [PDF]
This study evaluated the in vitro and in vivo antioxidant activities of puerarin (PUE) and β-lactoglobulin (β-lg). The results of the in vitro antioxidant assay revealed that the DPPH and ABTS radical scavenging rates of the PUE/β-lg complex were ...
Bo Ma +6 more
doaj +2 more sources
Puerarin Attenuates the Cytotoxicity Effects of Bisphenol S in HT22 Cells by Regulating the BDNF/TrkB/CREB Signaling Pathway [PDF]
Bisphenol S (BPS) is a widespread environmental endocrine disrupter that can cause hepatotoxicity, neurotoxicity and negative effects on reproduction. Puerarin (PUE) has been found to have anti-inflammatory, antioxidant, and neuroprotective properties ...
Meilin Qin +6 more
doaj +2 more sources
Puerarin prevents cadmium-induced endoplasmic reticulum stress via SIRT1-dependent PERK-CHOP pathway in HepG2 cells [PDF]
Cadmium (Cd) is a high-risk heavy metal that induces oxidative stress, endoplasmic reticulum (ER) stress and inflammation, damaging organs such as the liver.
Huang Di +7 more
doaj +2 more sources
Puerarin Targets HIF-1α to Modulate Hypoxia-Related Sphingolipid Metabolism in Diabetic Hepatopathy via the SPTLC2/Ceramide Pathway [PDF]
Background and Objectives: Diabetic hepatopathy, characterized by hepatic hypoxia and metabolic dysregulation, has a rising global incidence and prevalence, with limited effective treatments.
Mangui Cai +7 more
doaj +2 more sources
Puerarin pretreatment provides protection against myocardial ischemia/reperfusion injury via inhibiting excessive autophagy and apoptosis by modulation of HES1 [PDF]
The study aimed to elucidate the underlying pharmacological mechanism of the traditional Chinese medicine Pue in ameliorating myocardial ischemia-reperfusion injury (MIRI), a critical clinical challenge exacerbated by reperfusion therapy.
Yong Yuan +8 more
doaj +2 more sources
Protein–polyphenol interactions influence emulsifying properties in both directions. Puerarin (PUE) is an isoflavone that can promote the formation of heat-set gels with whey protein isolate (WPI) through hydrogen bonding.
Yejun Zhong +6 more
doaj +1 more source
Phase Unwrapping Error Correction Based on Multiple Linear Regression Analysis
Fringe projection profilometry (FPP) is prone to phase unwrapping error (PUE) due to phase noise and measurement conditions. Most of the existing PUE-correction methods detect and correct PUE on a pixel-by-pixel or partitioned block basis and do not make
Zhuang Lv +8 more
doaj +1 more source
Long-term trend and interannual variability of precipitation-use efficiency in Eurasian grasslands
Precipitation-use efficiency (PUE) is an important ecosystem indicator of the efficiency of carbon–water conversion. The trend and interannual variation of precipitation-use efficiency (PUE) response to climatic factors provide a theoretical foundation ...
Tianyou Zhang +10 more
doaj +1 more source

