Results 1 to 10 of about 6,488 (202)
Effect of puerarin on human choriocarcinoma cells
Open Medicine, 2015 Objective: To discuss the effect of puerarin on human choriocarcinoma cells. Methods: Survival rates under puerarin monotherapy, fluorouracil (5-FU) monotherapy and puerarin in combination with 5-FU were detected by MTT assay.
Bao Lidao +5 more
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Puerarin Suppress Apoptosis of Human Osteoblasts via ERK Signaling Pathway [PDF]
International Journal of Endocrinology, 2013 Puerarin, the main isoflavone glycoside extracted from Radix Puerariae, is an isoflavone traditional Chinese herb. Previous studies have demonstrated that puerarin could regulate osteoblast proliferation and differentiation to promote bone formation ...
Ling-juan Liu +6 more
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Combined Effects of Puerarin and Adipose‐Derived Stem Cells on Alveolar Bone Preservation and Inflammation Control in Periodontitis Through p38MAPK Modulation [PDF]
Kaohsiung Journal of Medical SciencesThis study evaluated the effects of puerarin and adipose‐derived stem cells (ADSCs), alone or combined, on p38MAPK activity, alveolar bone preservation, and inflammatory responses in a rat periodontitis (PD) model and in vitro.
Ting Yang, Xu Zhang, Liang‐Fu Zhang
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Puerarin inhibits EMT induced by oxaliplatin via targeting carbonic anhydrase XII
Frontiers in Pharmacology, 2022 Puerarin is a flavonoid molecule that widely exists in various plants. Puerarin has been reported to exhibit anti-tumor effects in various cancers. However, its exact underlying pharmacological mechanism is unclear.
Xindong Chen +8 more
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Puerarin Attenuates Diabetic Nephropathy by Promoting Autophagy in Podocytes
Frontiers in Physiology, 2020 Puerarin, an active compound of radix puerariae, is a major compound used in Chinese herbal medicines to treat patients with diabetic nephropathy (DN).
Xueling Li +7 more
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Molecular Mechanism of Puerarin Against Diabetes and its Complications
Frontiers in Pharmacology, 2022 Puerarin is a predominant component of Radix Puerarin. Despite its anti-tumor and anti-virus effects and efficacy in improving cardiovascular or cerebrovascular diseases and preventing osteoporosis, it has been shown to protect against diabetes and its ...
Yi-ling Bai +3 more
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Puerarin induces platinum-resistant epithelial ovarian cancer cell apoptosis by targeting SIRT1
Journal of International Medical Research, 2021 Objective Previous investigations indicated the anticancer activity of puerarin. The current study aimed to evaluate the effect and molecular mechanisms of puerarin in chemotherapy-resistant ovarian cancer cells.
Jianxiu Duan +4 more
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Puerarin: A Potential Therapeutic for SARS-CoV-2 and Hantavirus Co-Infection
Frontiers in Immunology, 2022 Patients with Hantavirus-caused epidemic hemorrhagic fever (EHF) are at risk of contracting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, there is currently no validated EHF/SARS-CoV-2 strategy.
Weizheng Liang +12 more
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BMC Complementary and Alternative Medicine, 2019 Background Puerarin exerts therapeutic effect on osteoporosis due to its inhibitory effect on the formation of osteoclasts. Puerarin is also widely established as an autophagy inhibitor.
Guoyou Zhang +3 more
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Molecules, 2018 Puerarin is a well-known traditional Chinese medicine which has been used for the treatment of cardiovascular diseases. Recently, a new advantageous crystal form of puerarin, puerarin-V, has been developed.
Xuguang Li +8 more
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