Results 11 to 20 of about 6,488 (202)

Effect of puerarin on bone formation [PDF]

open access: yesOsteoarthritis and Cartilage, 2007
Puerarin is one of the major phytoestrogens isolated from Pueraria lobata, a Chinese medicine known as Gegen. Our laboratory compared the amount of new bone produced by puerarin in collagen matrix (carrier) to that produced by the collagen matrix alone.Eighteen bone defects, 5mm by 10mm were created in the parietal bone of nine New Zealand White ...
Rabie, B, Wong, R
openaire   +6 more sources

Biotransformation of puerarin into puerarin-6″-O-phosphate by Bacillus cereus

open access: yesJournal of Industrial Microbiology and Biotechnology, 2012
Abstract The biotransformation of puerarin catalyzed by Bacillus cereus NT02 was studied. A primary screening was carried out using 307 strains of bacteria isolated from soil which were able to grow in the presence of puerarin. Strain NT02, identified as B. cereus, was able to convert puerarin into puerarin-6″-O-phosphate.
Lijuan, Yu   +5 more
openaire   +3 more sources

Puerarin

open access: yes, 2018
Aims: To assess the effect (week 12/week 24) of puerarin on carotid intima-media thickness (CIMT) in rheumatoid arthritis (RA). Methods: In the open, controlled, randomized and parallel-group comparison study, 119 consecutive RA patients under routine
Yue-Rong Zhao   +3 more
openaire   +2 more sources

Lignin/Puerarin Nanoparticle-Incorporated Hydrogel Improves Angiogenesis through Puerarin-Induced Autophagy Activation

open access: yesInternational Journal of Nanomedicine, 2023
Puerarin is the main isoflavone extracted from Radix Puerariae lobata (Willd.) and exerts a strong protective effect on endothelial cells. This isoflavone also exerts proven angiogenic effects; however, the potential underlying mechanism has not been fully explored.
Yingjing Pan   +8 more
openaire   +5 more sources

Comparative Pharmacokinetic Profiles of Puerarin in Rat Plasma by UHPLC-MS/MS after Oral Administration of Pueraria lobata Extract and Pure Puerarin

open access: yesJournal of Analytical Methods in Chemistry, 2020
Puerarin is the main biologically active isoflavone in Pueraria lobata and has a wide range of biological activities. However, due to its poor water solubility and low oral bioavailability, its clinical applications are restricted. Compared with puerarin,
Guozhe Zhang   +4 more
doaj   +2 more sources

Enzymatic Synthesis of Novel and Highly Soluble Puerarin Glucoside by Deinococcus geothermalis Amylosucrase

open access: yesMolecules, 2022
Puerarin (daidzein-8-C-glucoside) is an isoflavone isolated from several leguminous plants of the genus Pueraria. Puerarin possesses several pharmacological properties; however, the poor solubility of puerarin limits its applications.
Hsiou-Yu Ding   +4 more
doaj   +2 more sources

Puerarin Acts Through Brain Serotonergic Mechanisms to Induce Thermal Effects

open access: yesJournal of Pharmacological Sciences, 2004
The present study was attempted to investigate the effect of puerarin, an isoflavone compound isolated from Pueraria lobata, on both the basal body temperature and pyrogenic fever in unanesthetized, restrained rats.
Fu-Shin Chueh   +3 more
doaj   +2 more sources

Metabolic profile of puerarin in rats after intragastric administration of puerarin solid lipid nanoparticles

open access: yesInternational Journal of Nanomedicine, 2013
Cheng-Feng Luo,1,2 Ning Hou,2,3 Juan Tian,1,2 Mu Yuan,2,3 Shi-Ming Liu,1,2 Long-Gen Xiong,1,2 Jian-Dong Luo,2,3 Min-Sheng Chen1,2,41The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, People's Republic of China; 2Guangzhou ...
Luo CF   +7 more
doaj   +6 more sources

Puerarin: a hepatoprotective drug from bench to bedside

open access: yesChinese Medicine
Pueraria is a time-honored food and medicinal plant, which is widely used in China. Puerarin, the main component extracted from pueraria, has a variety of pharmacological characteristics.
Yi-Xiang He   +9 more
doaj   +2 more sources

Puerarin attenuates hypoxia-resulted damages in neural stem cells by up-regulating microRNA-214

open access: yesArtificial Cells, Nanomedicine, and Biotechnology, 2019
Puerarin has been reported to be useful in protection against hypoxia-induced injury. In our current study, we attempted to explore the protective effects of puerarin against hypoxia-caused damages in neural stem cells (NSCs).
Baoying Wang, Wenna Ma, Huiyu Yang
doaj   +2 more sources

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