Results 41 to 50 of about 6,488 (202)

Effects of dietary puerarin on growth, digestive enzyme, antioxidant capacity, immune and liver health of Acanthopagrus latus

Aquaculture Reports
This study was conducted to investigate the effects of puerarin on growth, digestive enzymes, antioxidant capacity, immunity and liver health of Acanthopagrus latus. Four diets were formulated: a control diet (C) and C supplemented with 200, 400, and 600 
Jianrong Ma, Lumin Kong, Zhangfan Huang, Xiujuan Wang, Fuqiang Quan, Xi Zhao, Zhenyu Yi, Hao Lin, Longhui Liu, Yunting Zhao, Wanting Luo, Sishun Zhou, Zhongbao Li   +12 more
doaj   +1 more source

Puerarin Improves Dexamethasone-Impaired Wound Healing In Vitro and In Vivo by Enhancing Keratinocyte Proliferation and Migration

Applied Sciences, 2021
The delayed and impaired wound healing caused by dexamethasone (DEX) is commonly reported. Puerarin, the major isoflavone found in Pueraria montana var. lobata (Willd.) Sanjappa & Pradeep promoted the wound healing process in diabetic rats.
Ly Thi Huong Nguyen, Sang-Hyun Ahn, Min-Jin Choi, In-Jun Yang, Heung-Mook Shin   +4 more
doaj   +1 more source

Nrf2 Is a Key Regulator on Puerarin Preventing Cardiac Fibrosis and Upregulating Metabolic Enzymes UGT1A1 in Rats

Frontiers in Pharmacology, 2018
Puerarin is an isoflavone isolated from Radix puerariae. Emerging evidence shown that puerarin possesses therapeutic benefits that aid in the prevention of cardiovascular diseases.
Shao-Ai Cai, Shao-Ai Cai, Ning Hou, Gan-Jian Zhao, Xia-Wen Liu, Ying-Yan He, Hai-Lin Liu, Yong-Quan Hua, Li-Rong Li, Yin Huang, Cai-Wen Ou, Cheng-Feng Luo, Min-Sheng Chen   +12 more
doaj   +1 more source

Puerarin alleviates sleep disorders in aged mice related to repairing intestinal mucosal barrier

Natural Products and Bioprospecting, 2023
More and more evidence suggests that puerarin, a potential remedy for gut inflammation, may have an ameliorative effect on sleep disturbances. However, the relationship between puerarin and sleep disruption has not been extensively researched. This study
Qing Tao, Jinhua Zhang, Qiao liang, Shiyu Song, Shuxia Wang, Xiaoming Yao, Qian Gao, Lei Wang   +7 more
doaj   +1 more source

Peran Puerarin terhadap Aktivitas Intra dan Ekstraseluler pada Kultur Human Umbilical Vein Endothelial Cells (HUVECs) Pasca Induksi Leptin

Journal of Experimental Life Science, 2011
Beberapa penelitian terkini menyebutkan bahwa leptin merupakan salah satu penyebab disfungsi endotel yang merupakan salah satu penyebab aterogenesis. Antioksidan puerarin diduga memiliki kemampuan untuk mencegah mekanisme aterogenesis yang distimulasi ...
Mochamad Sasmito Djati, Satuman Satuman, Sri Widyarti, Erly Nur Aisyah, Noer Hasanah, Eko Puji Astuti, Ririn Rochmawati   +6 more
doaj   +1 more source

Theoretical study on the glycosidic C–C bond cleavage of 3’’-oxo-puerarin

Scientific Reports, 2023
Puerarin, daidzein C-glucoside, was known to be biotransformed to daidzein by human intestinal bacteria, which is eventually converted to (S)-equol. The metabolic pathway of puerarin to daidzein by DgpABC of Dorea sp. PUE strain was reported as puerarin (
Jongkeun Choi, Yongho Kim, Bekir Engin Eser, Jaehong Han   +3 more
doaj   +1 more source

Self‐Amplified Activatable Fluorescent Probe for Early Diagnosis of Acute Kidney Injury and High‐Throughput Screening of Natural Protectants

Advanced Science, EarlyView.
The PS‐QRC nanoprobe employs L‐serine as a targeting ligand for kidney injury molecule‐1 (KIM‐1) to achieve accumulation in injured renal tissues. Upon activation by reactive oxygen species (ROS), it undergoes a self‐amplifying cascade to release fluorophores for near‐infrared fluorescence (NIRF) imaging, enabling ultra‐early diagnosis of acute kidney ...
Yahui Chen, Meihong Liu, Mengchao Ding, Ye Liu, Chuanxu Zhu, Mingye Gong, Zhixuan Huang, Yi Zhang, Wei Xue, Youyong Yuan, Kewei Wang   +10 more
wiley   +1 more source

Pharmacokinetics and drug delivery systems for puerarin, a bioactive flavone from traditional Chinese medicine

Drug Delivery, 2019
Pueraria lobata (Willd.) Ohwi is a medicinal and edible homologous plant with a long history in China. Puerarin, the main component isolated from the root of Pueraria lobata, possesses a wide range of pharmacological properties. Daidzein and glucuronides
Liang Zhang
doaj   +1 more source

From nature to nanoscale: advances, challenges, and preclinical translation of nanofiber drug delivery systems containing plant‐derived active ingredients

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Since the early 1960s, nanotechnology has been a critical area of science, allowing for the development of sophisticated nanomaterials. Nanofibers, one of the most widely used nanotechnological drug delivery systems, have emerged as a highly versatile platform within modern pharmaceutical sciences.
Heybet Kerem Polat, Yasin Turanlı, Nihat Kurt, Sefa Gözcü, Emre Tunçel, Hilal Bacanak, Eren Aytekin, Sedat Ünal   +7 more
wiley   +1 more source

Lipase-catalyzed synthesis of laurate esters from puerarin and its β-D-fructofuranosyl-(2→6)-puerarin derivative

This study investigates the transesterification of isoflavones puerarin and β-D-fructofuranosyl-(2→6)-puerarin to enhance their lipophilicity for specific pharmacological applications.
Arrizon, Javier, Torres-Tolentino, José Guadalupe, José-Guadalupe Torres-Tolentino (18280132), Hernández, Lázaro, Campos, Amador, Plou, Francisco J., Amador Campos (18280129), Lázaro Hernández (11145982), Casas-Godoy, Leticia, Leticia Casas-Godoy (11145979), Francisco J. Plou (2070418), Sandoval, Georgina, Georgina Sandoval (4784430), Javier Arrizon (11145994)   +13 more
core   +2 more sources