Results 51 to 60 of about 6,488 (202)

Analysis of Carbohydrates and Glycoconjugates by Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry: An Update for 2023–2024

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley   +1 more source

Upregulation of UDP-Glucuronosyltransferases 1a1 and 1a7 Are Involved in Altered Puerarin Pharmacokinetics in Type II Diabetic Rats

Molecules, 2018
Puerarin is an isoflavonoid extracted from Pueraria lobata roots, and displays a broad range of pharmacological activities, including antidiabetic activity. However, information about the pharmacokinetics of puerarin in diabetics is scarce.
Songtao Dong, Maofan Zhang, Huimin Niu, Kunyu Jiang, Jialei Jiang, Yinglin Ma, Xin Wang, Shengnan Meng   +7 more
doaj   +1 more source

Effects of a surface topography composite with puerariae radix on human STRO-1-positive stem cells [PDF]

, 2010
Human skeletal stem cells (STRO-1 positive/STRO-1+) respond to different topographical features in various ways. On a flat surface these cells spread and tend to develop a fibroblast-like morphology.
Burgess, K.E.V., Hart, Andrew, Burchmore, R., Burchmore, Richard, Hart, A., Riehle, M.O., Dalby, M.J., Oreffo, R.O., Jayawardena, Kamburapola, Jayawardena, K., Kantawong, F., Burgess, Karl E.V., Riehle, Mathias O., Oreffo, Richard O., Kantawong, Fahsai, Dalby, Matthew J.   +15 more
core   +1 more source

Multitarget Regulatory Mechanisms and Research Advances of Plant‐Derived Bioactive Ingredients in Hypertension Prevention and Management

Phytotherapy Research, EarlyView.
Schematic overview of the multi‐target and multi‐pathway mechanisms of PDBI in the prevention and management of hypertension. ABSTRACT Hypertension remains a major global risk factor for cardiovascular diseases, yet current treatments face challenges such as suboptimal blood pressure control and inadequate organ protection.
Qiqi Deng, Yonglin Zhang, Jing Pan, Jing Luo, Hualin Sun, Chaonian Li, Li Li   +6 more
wiley   +1 more source

Puerarin alleviates renal ischemia/reperfusion injury by inhibiting apoptosis and endoplasmic reticulum stress via Nrf2/HO-1 pathway [PDF]

Iranian Journal of Basic Medical Sciences
Objective(s): To explore the effects of puerarin on renal ischemia/reperfusion injury and the possible mechanism.Materials and Methods: The experimental mice were injected with puerarin (50 or 100 mg/kg) per day or equal sterile saline by intraperitoneal
Jingsong Wang, Qingyuan Zheng, Jun Jian, Xiuheng Liu, Zhiyuan Chen, Shanshan Wan, Lei Wang   +6 more
doaj   +1 more source

Puerarin Alleviates Depression-Like Behavior Induced by High-Fat Diet Combined With Chronic Unpredictable Mild Stress via Repairing TLR4-Induced Inflammatory Damages and Phospholipid Metabolism Disorders

Frontiers in Pharmacology, 2021
Puerarin has been reported as a potential agent for neuro-inflammatory disorders. However, there have been no reports of using puerarin for the treatment of depression based on Toll-like receptor 4 (TLR4)–mediated inflammatory injury.
Li-Na Gao, Li-Na Gao, Maocai Yan, Lirun Zhou, Lirun Zhou, Jian’an Wang, Chunmei Sai, Yingjie Fu, Yang Liu, Lin Ding   +9 more
doaj   +1 more source

Plant‐Derived Natural Product Nanodelivery System in Cancer Therapy

Phytotherapy Research, EarlyView.
This review comprehensively summarizes the recent progress and emerging concepts in nanotechnology‐based delivery systems for plant‐derived natural products, with a particular focus on their application in precision cancer therapy. ABSTRACT Plant‐derived natural products have emerged as important sources of anticancer agents because of their diverse ...
Changqi Shi, LuLu Zhang, Lan Yan, Qi Geng, Li Li, Xiaojuan He, Ning Zhao, Yong Tan, Xiaomeng Zhang, Cheng Lu   +9 more
wiley   +1 more source

Effects and mechanism of puerarin on lactation of postpartum hypogalactia mice [PDF]

Iranian Journal of Basic Medical Sciences
Objective(s): Insufficient breast milk supply is a common reason cited for discontinuing breastfeeding prematurely. Natural galactagogues offer promise as a solution for mothers with low milk production.
Ya-jie Yang, Bing-qing Liu, Yang Jiang, Man-yu Zhou, Re-yi-la Tuerxun, Hong-shuang Liu, Yan Liao   +6 more
doaj   +1 more source

Protective Potentials of Natural Products Against Vascular Dementia: A Comprehensive Review of Experimental Studies

Phytotherapy Research, EarlyView.
ABSTRACT Vascular dementia (VaD), accounting for up to 20% of dementia cases globally, is primarily driven by chronic cerebral hypoperfusion (CCH), which leads to progressive cognitive impairment. Despite the increasing prevalence of VaD, effective treatments remain limited.
Jung‐Hoon Kim, Yongtaek Oh, Suin Cho
wiley   +1 more source

Integrating network pharmacology and experimental verification to explore the mechanism of puerarin against oliguria in acute alcoholism

Frontiers in Pharmacology, 2022
Purpose: This study was designed to evaluate the pharmacological mechanisms of puerarin against oliguria in acute alcoholism via network pharmacology analysis combined with experimental verification.Methods: First, this study established an acute ...
Mei-Xuan Wan, Xian-Jun Huang, Xue Li, Juan Suan, Li Xu, Li Xu   +5 more
doaj   +1 more source