Results 91 to 100 of about 15,600,345 (296)

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

Modeling of Bond Stress–Slip Relationships of a Strand in Concrete during Steam Curing

open access: yesInternational Journal of Concrete Structures and Materials, 2017
The restrained thermal expansion of a pretensioned strand causes thermal prestress loss during steam curing until sufficient bond strength develops. The amount of thermal prestress loss is directly related to the characteristics of the interfacial bond ...
Chadon Lee   +3 more
doaj   +1 more source

Pull-out tests in presence of high level of corrosion [PDF]

open access: yes, 2014
Bond between steel and concrete deeply influences the structural behaviour of reinforced concrete structures. In the present work, local bond-slip behaviour is analysed in presence of corrosion of reinforcing bar embedded in concrete. The results of the tests on concrete cubes with side of 120 mm reinforced with ribbed steel bars with diameter of 12 mm
MANCINI, Giuseppe   +3 more
openaire   +2 more sources

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Materiales Compuestos ligeros basados en yeso con refuerzo de fibra de cascarilla de arroz y poliestireno

open access: yesInformador Técnico, 2016
Gypsum matrix composites were made with rice husk and polystyrene particles in order to obtain lightweight materials. The composites were mechanically characterized, and morphologically analyzed by Scanning Electron ...
Juan David Pardo   +3 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Mechanical Pull-Out Test of a New Hybrid Fixture-Abutment Connection: An In Vitro Study. [PDF]

open access: yesMaterials (Basel), 2021
D'Addazio G   +6 more
europepmc   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

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