Results 31 to 40 of about 54,253 (241)

Nanoparticle Deposition in Rhythmically Moving Acinar Models with Interalveolar Septal Apertures

Nanomaterials, 2019
Pulmonary delivery of nanomedicines has been extensively studied in recent years because of their enhanced biocompatibility, sustained-release properties, and surface modification capability.
Jinxiang Xi, Mohamed Talaat
doaj   +1 more source

Clinical biological and genetic heterogeneity of the inborn errors of pulmonary surfactant metabolism [PDF]

, 2001
Pulmonary surfactant is a multimolecular complex located at the air-water interface within the alveolus to which a range of physical (surface-active properties) and immune functions has been assigned. This complex consists of a surface-active lipid layer
Griese, Matthias, de Blic, Jacques, Bahuau, Michael, Tredano, Mohammed, Fournet, Jean-Christophe, Elion, Jacques   +5 more
core   +1 more source

Therapeutic sildenafil inhibits pulmonary damage induced by cigarette smoke exposure and bacterial inhalation in rats

Pharmaceutical Biology, 2020
Context Clinical reports showed sildenafil beneficial therapy on severe chronic obstructive pulmonary disease (COPD) with pulmonary hypertension (PH) patients.
Zhouxin Ren, Jiansheng Li, Junling Shen, Haibin Yu, Xiaofeng Mei, Peng Zhao, Zhenya Xiao, Wanliu Wu   +7 more
doaj   +1 more source

Molecular and pathological identification of ovine pulmonary adenomatosis at Mosul city abattoirs [PDF]

Iraqi Journal of Veterinary Sciences
Ovine Pulmonary adenomatosis OPA is a frequent condition that affects small ruminants, characterized by inflammation of the lung parenchyma, and causes polyp-like hyperplasia of the epithelium lining the alveoli and interstitial tissue like bronchi.
Osama Z. Jiad, Ahmed M. Al-Saidya
doaj   +1 more source

Histopathological Study of Cyclosporine Pulmonary Toxicity in Rats

Journal of Toxicology, 2016
Cyclosporine is considered one of the common worldwide immunosuppressive drugs that are used for allograft rejection prevention. However, articles that address adverse effects of cyclosporine use on the vital organs such as lung are still few. This study
Said Said Elshama, Ayman El-Meghawry EL-Kenawy, Hosam-Eldin Hussein Osman   +2 more
doaj   +1 more source

IGF1R controls mechanosignaling in myofibroblasts required for pulmonary alveologenesis

JCI Insight, 2021
Ventilation throughout life is dependent on the formation of pulmonary alveoli, which create an extensive surface area in which the close apposition of respiratory epithelium and endothelial cells of the pulmonary microvascular enables efficient gas ...
Hua He, John Snowball, Fei Sun, Cheng-Lun Na, Jeffrey A. Whitsett   +4 more
doaj   +1 more source

Diffuse alveolar hemorrhage as a manifestation of Behçet disease

Reumatismo, 2013
Diffuse alveolar hemorrhage (DAH) is a rare life-threatening condition which refers to the presence of red blood cells within alveoli deriving from hemorrhage originating in the pulmonary microvasculature. It differs from alveolar filling, in which blood
V. Grosso, E. Boveri, L. Bogliolo, C. Montecucco, R. Caporali   +4 more
doaj   +1 more source

Activation of ERBB4 Pathway Inhibits Pathological Transdifferentiation of Lung Epithelial Progenitors into CD66c+ Basal Cells in Severe Lung Injury

Advanced Science, EarlyView.
In fibrotic distal lung regions, CD66c+ basal cells emerge as a pathological state. Using human distal lung organoids, this study identifies CD66c+ basal cells as a pro‐fibrotic state arising through transdifferentiation from secretory, AT2, and basal cells.
Kaijun Lin, Xinran Deng, Haonan Wang, Yamei Jiang, Jian Sun, Hailin Ding, Ming Ye, Xiaoting Wang, Yu Wang, Li Yuan, Zhenju Song, Xinhua Lin, Shenfei Sun, Ning Jiang   +13 more
wiley   +1 more source

Pulmonary Edema: A Pictorial Review of Imaging Manifestations and Current Understanding of Mechanisms of Disease

European Journal of Radiology Open, 2020
Pulmonary edema is a common clinical entity caused by the extravascular movement of fluid into the pulmonary interstitium and alveoli. The four physiologic categories of edema include hydrostatic pressure edema, permeability edema with and without ...
Maria Barile
doaj   +1 more source

Proposed cardio-pulmonary model to investigate the effects of COVID-19 on the cardiovascular system

Heliyon, 2023
In this paper, we propose a new mathematical model of cardiovascular system coupled with a respiratory system to study the effects of COVID-19 on global blood circulation parameters using the lumped parameters model.
R.T. Djoumessi, I.P. Dongmo Vougmo, J.S. Tadjonang Tegne, F.B. Pelap   +3 more
doaj   +1 more source