Results 61 to 70 of about 1,155,700 (284)

Idiopathic pulmonary hemosiderosis

open access: yesJournal of Postgraduate Medicine, 2011
Idiopathic pulmonary hemosiderosis (IPH) is a rare disorder (triad of iron-deficiency anemia, hemoptysis, and alveolar infiltrates). A 3-year-old male presented with mild fever, breathlessness, dry cough, and bluish nail discoloration for 8 days.
Bhatia, S.   +3 more
openaire   +3 more sources

Mechanical Stress Induced NOX2 Promotes Endothelial Dysfunction in Ventilator‐Induced Lung Injury: Potential Treatment with Quercetin

open access: yesAdvanced Science, Volume 12, Issue 28, July 24, 2025.
Abnormal mechanical stretch induced by mechanical ventilation (MV) disrupts endothelial junctions via the NOX2/ROS/CaMKII/ERK1/2 axis both in human aortic endothelial cells (HAECs) in vitro and in ventilator‐induced lung injury (VILI) in mice. Quercetin, an antioxidant predicted to bind to NOX2, can effectively prevent mechanical stretch‐induced ...
Tao Jiang   +8 more
wiley   +1 more source

Transient Receptor Potential (TRP) Channels in Airway Toxicity and Disease: An Update

open access: yesCells, 2022
Our respiratory system is exposed to toxicants and pathogens from both sides: the airways and the vasculature. While tracheal, bronchial and alveolar epithelial cells form a natural barrier in the airways, endothelial cells protect the lung from perfused
Isabel Müller   +5 more
doaj   +1 more source

Polarized Helium to Image the Lung [PDF]

open access: yes, 2005
The main findings of the european PHIL project (Polarised Helium to Image the Lung) are reported. State of the art optical pumping techniques for polarising ^3He gas are described. MRI methodological improvements allow dynamical ventilation images with a
Leduc, Michèle, Nacher, Pierre-Jean
core   +4 more sources

Inhalable Artificial Polymeric Nucleases Degrading Neutrophil Extracellular Trap‐DNAs and Alleviating Pulmonary Fibrosis

open access: yesAdvanced Science, EarlyView.
Pulmonary fibrosis (PF) is promoted by NETs that induce fibroblast activation. PEG‐PIm, a polymeric artificial DNase is reported that efficiently degrades NET‐DNA via phosphodiester bond hydrolysis. Inhalation of PEG‐PIm in a mouse PF model prevents fibroblast activation and fibrosis progression, offering a promising therapeutic strategy for NET ...
Yibo Du   +7 more
wiley   +1 more source

A study of spectrum of pulmonary pathology and expression of thyroid transcription factor-1 during neonatal period

open access: yesIndian Journal of Pathology and Microbiology, 2018
Context: Neonatal period is the single most hazardous period of life. The major causes of neonatal death are prematurity and respiratory distress syndrome. We report a series of neonatal autopsies in our Neonatal Intensive Care Unit with special emphasis
Indranil Das   +5 more
doaj   +1 more source

Alveolar cells under mechanical stressed niche: critical contributors to pulmonary fibrosis

open access: yesMolecular Medicine, 2020
Pulmonary fibrosis arises from the repeated epithelial mild injuries and insufficient repair lead to over activation of fibroblasts and excessive deposition of extracellular matrix, which result in a mechanical stretched niche.
Juntang Yang   +3 more
doaj   +1 more source

A case of diffuse alveolar hemorrhage after tonsillectomy -A case report- [PDF]

open access: yesKorean Journal of Anesthesiology, 2012
Diffuse alveolar hemorrhage (DAH) is an acute, life-threatening event. The blood-gas barrier must be very thin to allow gas exchange and is therefore subjected to high mechanical stresses when the capillary pressure rises.
Jin Pyeong Kim   +3 more
doaj   +1 more source

AI‐Driven Microphysiological Systems for Advancing Nanoparticle Therapeutics

open access: yesAdvanced Intelligent Systems, EarlyView.
This review outlines recent advances in integrating artificial intelligence with microphysiological systems for nanoparticle evaluation. It highlights data‐driven optimization, image‐based prediction, and AI‐enabled analysis frameworks that advance translational research and support the development of personalized nanomedicine. Nanoparticles (NPs) play
Yedam Lee   +3 more
wiley   +1 more source

Pulmonary surfactant system [PDF]

open access: yesEurasian Journal of Veterinary Sciences
Pulmonary surfactant, a phospholipid-protein complex that lines the alveoli and small airways of the lungs, is secreted by type ll alveolar epithelial cells. Recognized functions of surfactant are (1) maintaining proper humidity of the alveolar wall; (2)
Zafer Durgun, Ercan Keskin
doaj  

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