Results 81 to 90 of about 75,385 (196)
British Journal of Clinical Pharmacology, EarlyView.Aerospace medicine required controlled terrestrial models to investigate influences of altered atmosphere conditions, such as hypoxia, on human health and performance. These models could potentially be expanded to encompass disease conditions or treatment targets regulated through hypoxia or hypercapnia.
Titiaan E. Post +4 more
wiley +1 more source
Physiological modeling of isoprene dynamics in exhaled breath [PDF]
, 2003 Human breath contains a myriad of endogenous volatile organic compounds (VOCs) which are reflective of ongoing metabolic or physiological processes.
King, Julian +8 more
core +4 more sources
Klotho Regulates Club Cell Senescence and Differentiation in Chronic Obstructive Pulmonary Disease
Cell Proliferation, EarlyView.We speculated lack of Klotho (KL) would aggravate club cell senescence, which contributes to COPD inflammation. In this study, we collected chronic obstructive pulmonary disease (COPD) lung tissue using single‐cell RNA sequencing (scRNA‐seq), revealing club cell heterogeneity and cellular senescence in COPD.
Min Li +5 more
wiley +1 more source
Internal Medicine Journal, EarlyView.ABSTRACT Connective tissue disease‐associated interstitial lung disease (CTD‐ILD) comprises a heterogenous group of conditions characterised by immune‐mediated fibro‐inflammatory pulmonary injury. Although the disease course is variable, CTD‐ILD can progress to respiratory failure and thus has a profound impact on morbidity and mortality.
Michael Hong +2 more
wiley +1 more source
Immunology, EarlyView.Antibiotic‐induced dysbiosis of the gut microbiota shifts host tryptophan metabolism and impairs the innate immune response during Pseudomonas aeruginosa pulmonary infection. (A) Eubiosis: During eubiosis, the intestinal microbiota metabolises tryptophan into indole metabolites, which keeps tryptophan levels within normal serum concentrations. However,
Camila Bernardo de Brito +19 more
wiley +1 more source
The Landscape of SPP1+ Macrophages Across Tissues and Diseases: A Comprehensive Review
Immunology, EarlyView.SPP1+ macrophages represent a conserved, disease‐associated population present across cancerous and non‐cancerous conditions, involved in immunosuppression, fibrosis, lipid metabolism, phagocytosis, and other cellular processes. This review highlights their shared molecular programmes across tissues, their interactions with stromal and immune cells ...
Alessandro Palma
wiley +1 more source
Focal Spot, Fall/Winter 2010/2011 [PDF]
, 2011 https://digitalcommons.wustl.edu/focal_spot_archives/1115/thumbnail ...
core +1 more source
Journal of Anatomy, EarlyView.The skin development in the gray short‐tailed opossum (Monodelphis domestica) has been examined using histological, morphometric, and μCT methods. During a long period of postnatal development, the structural differentiation of the skin results in a functional shift from transcutaneous gas exchange to thermoregulation in later life. Abstract Marsupials
Kirsten Ferner
wiley +1 more source
The Evolution of Cell Communication: The Road not Taken. [PDF]
, 2009 In the post-genomic era the complex problem of evolutionary biology can be tackled from the top-down, the bottom-up, or from the middle-out. Given the emergent and contingent nature of this process, we have chosen to take the latter approach, both as a ...
Rehan, VK, Torday, JS
core +1 more source
Journal of Small Animal Practice, EarlyView.Objectives To compare the diagnostic yield of endobronchial Wang™ needle aspiration to that of bronchial brushing and forceps biopsy for canine tracheal and endobronchial masses and submucosal infiltrations examined by fiberoptic bronchoscopy. Materials and Methods Flexible fiberoptic bronchoscope‐guided bronchial brushing, forceps biopsy, and ...
D. De Lorenzi +4 more
wiley +1 more source