Results 101 to 110 of about 53,184 (204)

Keeping it together: Pulmonary alveoli are maintained by a hierarchy of cellular programs. [PDF]

Bioessays, 2015
Logan CY, Desai TJ.
europepmc   +1 more source

TGF‐β1 Directly Sensitizes Capsaicin‐Sensitive Lung Vagal Neurons to Promote Airway Hypersensitivity

Acta Physiologica, Volume 242, Issue 10, October 2026.
ABSTRACT Aim Transforming growth factor‐β1 (TGF‐β1) is a pleiotropic cytokine implicated in the pathogenesis of inflammatory airway diseases such as asthma. Airway hypersensitivity (AHS), arising from sensitization of capsaicin‐sensitive lung vagal (CSLV) afferents, is a hallmark of these airway diseases.
Yueh‐Yin Chen, Nai‐Ju Chan, Chun‐Chun Hsu   +2 more
wiley   +1 more source

The lung is more than an organ of gas exchange: immunocompetency, platelets and implications for drug discovery

British Journal of Pharmacology, Volume 183, Issue 20, Page 5999-6006, October 2026.
Abstract The lungs have for a long time been recognised as having pharmacological significance as a specific organ to modulate the pharmacokinetics of endogenous substances needed to maintain homeostasis. The lungs are therefore the site of action of certain drugs that act on these homeostatic processes, resulting in systemic effects on the ...
Simon C. Pitchford
wiley   +1 more source

Updates in COPD Management: From Inflammatory Pathways to Targeted Therapies

European Journal of Clinical Investigation, Volume 56, Issue 10, October 2026.
COPD is a heterogeneous disease driven by overlapping neutrophilic and eosinophilic inflammatory pathways. This review highlights the shift from symptom‐based treatment toward phenotype‐ and biomarker‐directed care. Blood eosinophils, FeNO, and IgE predict corticosteroid responsiveness and identify candidates for biologic therapy.
Sasha Raman, Sreya Rahman, Francesca Polverino, Muhammad Adrish   +3 more
wiley   +1 more source

Pulmonary Alveolar Microlithiasis with Klippel-Feil Syndrome: The Eye Does Not See What The Mind Does Not Know

Journal of Bahria University Medical and Dental College, 2015
Pulmonary alveolar microlithiasis is a rare idiopathic disorder characterized by multiple microliths in the alveoli. Chest X-ray examination show miliary mottling mimicking Tuberculosis. Klippel-Feilsyndromeinclude short neck, low hairline and decreased
Muhammad Tahir Khadim, Nisar Ahmed, Asif Asghar, Rahat Rao, Kiran Nauman, Syed Raza Jaffar   +5 more
doaj  

Pulmonary Alveolar Microlithiasis: A Rare Case Report

Iranian Journal of Medical Sciences, 2013
Pulmonary alveolar microlithiasis is an uncommon infiltrative pulmonary disease characterized by deposition of microliths in the alveoli. We present the case of a young adult with complaints of shortness of breath on exertion.
Kaleem Ahmad, Mukesh Kumar Gupta, Kanchan Dhungel, Panna Lal Sah, Sajid Ansari, Raj Kumar Rauniyar   +5 more
doaj  

Mycobacterium tuberculosis resisters despite HIV exhibit activated T cells and macrophages in their pulmonary alveoli. [PDF]

J Clin Invest
Dallmann-Sauer M, Fava VM, Malherbe ST, MacDonald CE, Orlova M, Kroon EE, Cobat A, Boisson-Dupuis S, Hoal EG, Abel L, Möller M, Casanova JL, Walzl G, Du Plessis N, Schurr E.   +14 more
europepmc   +1 more source

Developmental Therapeutics for Alveolar Generation and Regeneration: Implications for Bronchopulmonary Dysplasia and Prematurity-Associated Lung Disease. [PDF]

Cells
Warburton D, Moats R, Parton LA, LaGamma EF, Niklas V.   +4 more
europepmc   +1 more source

CFTR in alveolar type 1 cells contributes to lung liquid secretion and host defense. [PDF]

JCI Insight
Suthakaran S, Homami S, Chavez D, Tang S, Moore SK, Sussman C, Zhang J, Britto CJ, Prince A, May AJ, Kathiriya JJ, Hook JL.   +11 more
europepmc   +1 more source

A compound heterozygous combination of SLC34A2 variants in pulmonary alveolar microlithiasis: A case report and literature review. [PDF]

J Int Med Res
Zou Z, Mei P, Yan L, Wu H, Xing Y, Ben X, Zhan W.   +6 more
europepmc   +1 more source