Results 81 to 90 of about 622,177 (374)

Analysis of the Characteristics of Patients Presenting with Exacerbation of Asthma to Emergency Care Units [PDF]

, 2015
Background:Fatal asthma remains a serious problem, and patient self-management of asthma is important to prevent exacerbation. To reduce the asthma mortality rate, we analyzed the characteristics of patients who visited an emergency care unit with ...
Department Of Pulmonary Medicine And Clinical Immunology Dokkyo Medical University:Department Of Pulmonary Medicine And Clinical Immunology Dokkyo Medical University, Department Of Respiratory Medicine, Dokkyo Medical University Koshigaya Hospital, Department Of Respiratory Medicine, Dokkyo Medical University Koshigaya Hospital:Department Of Pulmonary Medicine And Clinical Immunology Dokkyo Medical University, Department Of Respiratory Medicine, Dokkyo Medical University Koshigaya Hospital:Department Of Pulmonary Medicine And Clinical Immunology Dokkyo Medical University, Department Of Respiratory Medicine, Dokkyo Medical University Koshigaya Hospital:Department Of Pulmonary Medicine And Clinical Immunology Dokkyo Medical University, Department Of Respiratory Medicine, Dokkyo Medical University Koshigaya Hospital:Department Of Pulmonary Medicine And Clinical Immunology Dokkyo Medical University, Department Of Respiratory Medicine, Dokkyo Medical University Koshigaya Hospital:Department Of Pulmonary Medicine And Clinical Immunology Dokkyo Medical University, Department Of Respiratory Medicine, Dokkyo Medical University Koshigaya Hospital:Department Of Pulmonary Medicine And Clinical Immunology Dokkyo Medical University, Department Of Respiratory Medicine, Dokkyo Medical University Koshigaya Hospital:Department Of Pulmonary Medicine And Clinical Immunology Dokkyo Medical University, Hideyuki Satoh, Kentaro Nakano, Kumiya Sugiyama, Naruo Yoshida, Ryosuke Souma, Shingo Tokita, Takeshi Fukuda, Tomoshige Wakayama, Yasutsugu Fukushima   +17 more
core   +1 more source

Palliative care for people with non-malignant lung disease: summary of current evidence and future direction [PDF]

, 2013
Background: The physical and psychosocial needs of patients with chronic non-malignant lung disease are comparable to those with lung cancer. This article will focus on chronic obstructive pulmonary disease, interstitial lung disease and cystic fibrosis ...
Boland, Jason, Martin, Jonathan, Ross, Joy R, Ross, Joy R., Wells, Athol U, Wells, Athol U.   +5 more
core   +1 more source

Successful management of refractory respiratory failure caused by avian influenza H7N9 and secondary organizing pneumonia: a case report and literature review

BMC Infectious Diseases, 2019
Backgroud Organizing pneumonia (OP) is a rare complication of influenza infection that has substantial morbidity. We report the first case of OP associated with avian influenza H7N9 infection that had significant improvement with corticosteroid treatment.
Hangyong He, Hao Wang, Xuyan Li, Xiao Tang, Bing Sun, Zhaohui Tong   +5 more
doaj   +1 more source

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

Molecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen, Chung‐Teng Wang, Jia‐Ming Chang, Ai‐Li Shiau, Gia‐Shing Shieh, Yau‐Lin Tseng, Yi‐Ting Yen, Tang‐Hsiu Huang, Li‐Hsin Cheng, Yu‐Chih Wu, Chao‐Liang Wu, Bing‐Hua Su, Pensee Wu   +12 more
wiley   +1 more source

Exogenous S100A4 Protein Attenuates Bleomycin-induced Pulmonary Fibrosis in Mice by Reducing the Levels of Fibroblast Growth Factors [PDF]

, 2016
Background and objective:The calcium-binding protein S100A4 belongs to the S100 family and is involved in fibrotic and inflammatory processes, in which tissue remodeling, cell motility, and epithelialmesenchymal transition play major roles.
Department Of Pulmonary Medicine And Clinical Immunology, Dokkyo Medical University:Department Of Pulmonary Medicine And Clinical Immunology, Dokkyo Medical University, Department Of Respiratory Medicine And Clinical Immunology, Dokkyo Medical University Koshigaya Hospital, Department Of Respiratory Medicine And Clinical Immunology, Dokkyo Medical University Koshigaya Hospital:Department Of Pulmonary Medicine And Clinical Immunology, Dokkyo Medical University, Department Of Respiratory Medicine And Clinical Immunology, Dokkyo Medical University Koshigaya Hospital:Department Of Pulmonary Medicine And Clinical Immunology, Dokkyo Medical University, Department Of Respiratory Medicine And Clinical Immunology, Dokkyo Medical University Koshigaya Hospital:Department Of Pulmonary Medicine And Clinical Immunology, Dokkyo Medical University, Department Of Respiratory Medicine And Clinical Immunology, Dokkyo Medical University Koshigaya Hospital:Department Of Pulmonary Medicine And Clinical Immunology, Dokkyo Medical University, Department Of Respiratory Medicine And Clinical Immunology, Dokkyo Medical University Koshigaya Hospital:Department Of Pulmonary Medicine And Clinical Immunology, Dokkyo Medical University, Department Of Respiratory Medicine And Clinical Immunology, Dokkyo Medical University Koshigaya Hospital:Department Of Pulmonary Medicine And Clinical Immunology, Dokkyo Medical University, Hirokuni Hirata, Kenya Kohyama, Kumiya Sugiyama, Masafumi Arima, Masamitsu Tatewaki, Mineaki Watanabe, Takeshi Fukuda, Vice President Of Dokkyo Medical University:Department Of Pulmonary Medicine And Clinical Immunology, Dokkyo Medical University, Yasutsugu Fukushima, Yoshiki Ishii   +17 more
core   +1 more source

Emerging respiratory viral infections: MERS-CoV and influenza [PDF]

, 2014
This article is made available for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source.
Al-Tawfiq, Jaffar A., Memish, Ziad A.
core   +1 more source

Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management

Molecular Oncology, EarlyView.
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez, Asieh Naderi, Kim‐Tuyen Huynh‐Dam, Vitali Sikirzhytski, Ioulia Chatzistamou, Hippokratis Kiaris   +5 more
wiley   +1 more source

Extracorporeal Membrane Oxygenation Supported Transbronchial Cryobiopsy in the Diagnosis of Severe Organizing Pneumonia: A Case Report

Frontiers in Medicine, 2022
This case report describes a 58-year-old, never-smoking housewife with chief complaints of progressively worsening cough, dyspnea, and intermittent fever, who was initially misdiagnosed with community-acquired pneumonia (CAP). However, her pulse oximetry
Xiaoyan Zhang, Yuqiong Wang, Yuqiong Wang, Yingying Feng, Ling Zhao, Yunxia Zhang, Hanbo Yang, Bin Xing, Wenlin Guo, Ting Sun, Qingyuan Zhan, Ye Tian   +11 more
doaj   +1 more source

Polydatin ameliorates ovalbumin‐induced asthma in a rat model through NCOA4‐mediated ferroautophagy and ferroptosis pathway

FEBS Open Bio, EarlyView.
In this research, a rat model of asthma was created using OVA, and polydatin served as an intervention. By inhibiting ferroautophagy mediated by NCOA4 and averting ferroptosis, polydatin has been demonstrated to reduce asthma. This work presents new ideas for investigating the mechanism of polydatin's ability to alleviate asthma, in addition to ...
Wei Li, Yuwei Tang, Wenkang Liu, Fang Fang, Jiepeng Wang, Chaoyi Fang   +5 more
wiley   +1 more source

Eosinophil and T Cell Markers Predict Functional Decline in COPD Patients [PDF]

, 2009
BACKGROUND. The major marker utilized to monitor COPD patients is forced expiratory volume in one second (FEV1). However, asingle measurement of FEV1 cannot reliably predict subsequent decline.
A Papi, AK Sullivan, AT Society, B Barcelo, B Meshi, BH Nelson, C Fletcher, CS Robbins, CS Robbins, DL Mueller, DW Perng, F Mor, G Rohde, GJ de Bree, J Chang, J Chang, JL Hankinson, L Lintomen, L Taraseviciene-Stewart, L Van Parijs, L Van Parijs, M Decramer, M Miller, M Saetta, M Saetta, MD Roth, N Tzanakis, NR Anthonisen, P Glader, PC Doherty, PD Ponath, PD Ponath, PJ Barnes, PT King, RO Crapo, RW Vandivier, S Chakrabarti, S Hodge, S Hodge, S Hodge, S Wei, T Seemungal, TC O'Shaughnessy, V Bocchino   +43 more
core   +4 more sources