Results 61 to 70 of about 468,103 (315)

Respiratory Diseases [PDF]

, 2012
Medicine is an ever-changing science. In this regard, Respiratory medicine is not an exception and has been evolving during recent years. As new research broadens our knowledge, advanced methods for diagnoses are better understood, providing genetic and ...

core   +2 more sources

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin, Binbin Xue, Dewei Xie, Jia Li, Juyuan Pan, Lanbing Zhu, Qiaowen Tong, Jing Lin, Ruofan Zhu, Xu Zhang, Junhui Xia, Xiang Li   +11 more
wiley   +1 more source

Long‐Term Efficacy of Immunotherapy in Autoimmune Autonomic Ganglionopathy—A 10‐Year Follow Up Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune autonomic ganglionopathy (AAG) is a rare but potentially treatable cause of severe autonomic failure. Evidence guiding long‐term immunotherapy, treatment sequencing, and residual autonomic impairment is limited. We evaluated long‐term treatment response, residual autonomic dysfunction, and relapse patterns in patients with
Giacomo Chiaro, Shiwen Koay, Gordon T. Ingle, Patricia McNamara, Laura Watson, Fion Bremner, Valeria Iodice   +6 more
wiley   +1 more source

Association of asthma and bronchiectasis: Mendelian randomization analyses and observational study

Respiratory Research
Background Previous studies have demonstrated that asthma is closely associated with bronchiectasis, however, the causal relationship between asthma and bronchiectasis has not been investigated in depth.
Rui Fan, Hao Qian, Jia-Yan Xu, Jia-Yi Wang, Yue Su, Jia-Wei Yang, Fang Jiang, Wei-Jun Cao, Jin-Fu Xu   +8 more
doaj   +1 more source

Adjunctive treatment with oral AKL1, a botanical nutraceutical, in chronic obstructive pulmonary disease

, 2014
Claire Brockwell,1 Sundari Ampikaipakan,1,2 Darren W Sexton,1 David Price,3,4 Daryl Freeman,5 Mike Thomas,6 Muzammil Ali,4 Andrew M Wilson1,21Norwich Medical School, University of East Anglia, Norwich, UK; 2Norfolk and Norwich University Hospital ...
Freeman, D, Wilson, AM, Thomas, Mike, Brockwell, Claire, Ampikaipakan, Sundari, Thomas M, Ampikaipakan, S, Ali, M, Sexton, Darren W., Freeman, Daryl, Brockwell C, Ampikaipakan S, Thomas, M., Wilson, Andrew M., Brockwell, C, Freeman D, Ali M, Sexton, DW, Sexton DW, Price, D, Price, David, Ali, Muzammil, Thomas, M, Price D, Wilson AM   +24 more
core   +1 more source

Evaluation of Digital Technologies for Home‐Based Assessment in People With Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller, Vanessa Vallejo, Mónica Povedano Panadés, Orla Hardiman, Véronique Danel‐Brunaud, Senda Ajroud‐Driss, Philippe Couratier, Jeremy Shefner, Anna Gokey, Mike DiCesare, Erin Lennox, Jens Praestgaard, Lucie Brujin, Peggy Allred, Ram Miller   +14 more
wiley   +1 more source

Evidence for Interleukin-17C governing interleukin-17A pathogenicity and promoting asthma endotype switching in bronchiectasis

Nature Communications
The management of bronchiectasis-asthma overlap (BAO) is an important clinical issue to be addressed. Little is known regarding the endotype of BAO. Here we recruit patients with a primary diagnosis of bronchiectasis and co-existing asthma. The levels of
Yu-Wei Zhang, Yu-Hua Wen, Ling Yang, Ying-Zhou Xie, Dong Weng, Xi-Yue Shen, Jing-Ge Ma, Hai-Wen Lu, Xiao-Li Sun, Shu-Yi Gu, Bei Mao, Ai Ge, Yue Su, Fang Jiang, You-Cun Qian, Jin-Fu Xu   +15 more
doaj   +1 more source

Extracellular matrix remodelling in COPD

European Respiratory Review, 2020
The extracellular matrix (ECM) of the lung plays several important roles in lung function, as it offers a low resistant pathway that allows the exchange of gases, provides compressive strength and elasticity that supports the fragile alveolar–capillary ...
Meropi Karakioulaki, Eleni Papakonstantinou, Daiana Stolz   +2 more
doaj   +1 more source

Overlap Syndrome in Respiratory Medicine: Asthma and Chronic Obstructive Pulmonary Disease

Journal of Cardio-Thoracic Medicine, 2014
Asthma and chronic obstructive pulmonary disease (COPD) are highly prevalent chronic diseases in the general population. Both are characterized by similar mechanisms: airway inflammation, airway obstruction, and airway hyperresponsiveness. However, the distinction between the two obstructive diseases is not always clear.
Corlateanu, Alexandru, Pripa, Valeria, Montanari, Gloria, Botnaru, Victor   +3 more
openaire   +4 more sources

Four patients with a history of acute exacerbations of COPD: implementing the CHEST/Canadian Thoracic Society guidelines for preventing exacerbations [PDF]

, 2015
This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if ...
Marciniuk, D, Goodridge, D, Bourbeau, J, Tsiligianni, I, Hull, S   +4 more
core   +1 more source