Results 51 to 60 of about 679,434 (313)

Utility and safety of airway stenting in airway stenosis after lung transplant: A systematic review

Frontiers in Medicine, 2023
BackgroundAirway complications seriously affect the clinical outcomes and long-term prognosis of lung-transplantation patients. Airway stenting provides effective palliation for patients with airway stenosis.
Zilin Wang, Bo Zhao, Mingming Deng, Run Tong, Yiding Bian, Qin Zhang, Gang Hou   +6 more
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

The Effect of Growth and Body Surface Area on Cardiopulmonary Exercise Testing: A Cohort Study in Preadolescent Female Swimmers

Children, 2023
Background: The performance of young swimmers is the result of a multifactorial process that is influenced by anthropometric characteristics and biological maturation.
Vasileios T. Stavrou, Eleni Karetsi, Konstantinos I. Gourgoulianis   +2 more
doaj   +1 more source

Lung volumes identify an at-risk group in persons with prolonged secondhand tobacco smoke exposure but without overt airflow obstruction. [PDF]

, 2018
IntroductionExposure to secondhand smoke (SHS) is associated with occult obstructive lung disease as evident by abnormal airflow indices representing small airway disease despite having preserved spirometry (normal forced expiratory volume in 1 s-to ...
Arjomandi, Mehrdad, Blanc, Paul D, Bos, Bruce, Elicker, Brett, Geerts, Jeroen, Gold, Warren M, Keene, Jason, Stiner, Rachel K, van Koeverden, Ian, Zeng, Siyang   +9 more
core   +2 more sources

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

FEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng, Souvik Datta, Derrick R. Samuelson   +2 more
wiley   +1 more source

The Correlation Between Body Fat Percentage and Peak Expiratory Flow in Children Aged 10-12 Years at SD Negeri 8 Dauh Puri [PDF]

, 2019
Background: The accumulation of fat decreases lung function. Peak expiratory flow is an indicator for assessing pulmonary function and can be used to identify the narrowing or obstruction of the airway. This study aimed to examine the correlation between
Indahswari, N. W. (Ni), Indrayani, A. W. (Agung), Thanaya, S. A. (Sayu), Wibawa, A. (Ari)   +3 more
core   +2 more sources

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Effects of postoperative antifungal therapy on the recurrence of Aspergillus infection after pulmonary aspergilloma resection: a prospective, randomized, controlled, single-center, 24-month, open-label, parallel group trial

BMC Infectious Diseases
Background Surgical resection is considered the most effective therapeutic method for pulmonary aspergilloma (PA), while the necessity of postoperative antifungal therapy remains controversial.
Jian Yang, Chan Liu, Jianxiong Li, Xianqiu Chen, Beibei Wang, Jing Zhang, Haifeng Wang, Deping Zhao, Yiming Zhou, Haomin Cai, Jin-fu Xu, Shuo Liang   +11 more
doaj   +1 more source

Successful rescue combination of extracorporeal membrane oxygenation, high-frequency oscillatory ventilation and prone positioning for the management of severe methicillin-resistant Staphylococcus aureus pneumonia complicated by pneumothorax: a case report and literature review

BMC Pulmonary Medicine, 2017
Background To describe the experience of combination therapy with extracorporeal membrane oxygenation(ECMO), high-frequency oscillatory ventilation(HFOV) and prone positioning in treating severe respiratory failure caused by community acquired ...
Hangyong He, Hao Wang, Xuyan Li, Xiao Tang, Rui Wang, Bing Sun, Zhaohui Tong   +6 more
doaj   +1 more source

Riociguat for the treatment of chronic thromboembolic pulmonary hypertension. [PDF]

, 2013
BACKGROUND: Riociguat, a member of a new class of compounds (soluble guanylate cyclase stimulators), has been shown in previous clinical studies to be beneficial in the treatment of chronic thromboembolic pulmonary hypertension. METHODS: In this phase 3,
CHEST-1 Study Group,, D'Armini, AM, Fritsch, A, Ghofrani, HA, Grimminger, F, Hoeper, MM, Jansa, P, Kim, NH, Mayer, E, Neuser, D, Simonneau, G, Wang, C, Weimann, G, Wilkins, MR   +13 more
core   +1 more source