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Pulmonary aspergillosis and mucormycosis in a patient with COVID-19

Medical Mycology Case Reports, 2021
Invasive pulmonary mucormycosis and aspergillosis are rare, life-threatening fungal infections. Most documented cases have been reported in patients with diabetes mellitus, neutropenia, or treatment with corticosteroids.
André K Johnson, Jon G Persichino
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Invasive pulmonary aspergillosis real-world outcomes: Clinical features and risk factors associated with increased mortality.

Medical Mycology, 2023
Invasive pulmonary aspergillosis is a severe fungal infection that primarily affects immunocompromised patients and is associated with high mortality. Contemporary clinical characteristics of invasive pulmonary aspergillosis and "real world" estimates ...
A. Henao-Martínez, M. Corbisiero, Ixchel T Salter, D. Chastain, G. Thompson   +4 more
semanticscholar   +1 more source

Pathogenesis and clinical features of chronic pulmonary aspergillosis – Is it possible to distinguish CNPA and CCPA clinically?

Journal of Infection and Chemotherapy, 2014
Background: The pathogenesis of chronic pulmonary aspergillosis (CPA) including chronic necrotizing pulmonary aspergillosis (CNPA), chronic cavitary pulmonary aspergillosis (CCPA), and simple aspergilloma (SA) has been poorly investigated.
Koichi Izumikawa, Takayoshi Tashiro, Takahiro Takazono   +2 more
exaly   +3 more sources

CAR T cells targeting Aspergillus fumigatus are effective at treating invasive pulmonary aspergillosis in preclinical models

Science Translational Medicine, 2022
Aspergillus fumigatus is a ubiquitous mold that can cause severe infections in immunocompromised patients, typically manifesting as invasive pulmonary aspergillosis (IPA). Adaptive and innate immune cells that respond to A.
M. Seif, T. K. Kakoschke, F. Ebel, M. Bellet, Nora Trinks, G. Renga, M. Pariano, L. Romani, Beeke Tappe, D. Espie, E. Donnadieu, Kerstin Hünniger, A. Häder, Markus Sauer, D. Damotte, M. Alifano, P. L. White, M. Backx, T. Nerreter, M. Machwirth, O. Kurzai, Sabrina Prommersberger, H. Einsele, M. Hudecek, J. Löffler   +24 more
semanticscholar   +1 more source

Invasive pulmonary aspergillosis

Revista Clínica Española (English Edition), 2020
AbstractInvasive pulmonary aspergillosis (IPA) remains difficult to diagnose and to treat. Most common risk factors are prolonged neutropenia, hematopoietic stem cell or solid organ transplantation, inherited or acquired immunodeficiency, administration of steroids or other immunosuppressive agents including monoclonal antibodies and new small ...
L A, Fernández-Bermejo, G, Ramírez-Olivencia   +1 more
openaire   +4 more sources

Pulmonary aspergillosis

The Netherlands Journal of Medicine, 2001
Aspergillus species are ubiquitous in the environment and are inevitably inhaled into the airways. Inhalation of Aspergillus conidia or mycelium fragments may result in colonisation of the airways. In susceptible hosts colonisation may subsequently cause disease.
J F, Tomee, T S, van der Werf
openaire   +2 more sources

Efficacy of 12-months oral itraconazole versus 6-months oral itraconazole to prevent relapses of chronic pulmonary aspergillosis: an open-label, randomised controlled trial in India.

Lancet. Infectious Diseases (Print), 2022
BACKGROUND Chronic pulmonary aspergillosis has a 5-year mortality of 50-80% globally, and the optimal duration of treatment for chronic pulmonary aspergillosis remains unclear.
I. Sehgal, S. Dhooria, V. Muthu, K. Prasad, A. Aggarwal, A. Chakrabarti, Hansraj Choudhary, M. Garg, R. Agarwal   +8 more
semanticscholar   +1 more source

Pulmonary Aspergillosis in the Acquired Immunodeficiency Syndrome

New England Journal of Medicine, 1991
BACKGROUND AND METHODS: Symptomatic pulmonary aspergillosis has rarely been reported in patients with the acquired immunodeficiency syndrome (AIDS). We describe the predisposing factors, the clinical and radiologic features, and the therapeutic outcomes ...
David W Denning, David A Stevens, Denning David W   +2 more
exaly   +2 more sources

The spectrum of pulmonary aspergillosis

Irish Journal of Medical Science, 1988
THIS paper is a retrospective study of thirty-nine patients with lung disease, caused by aspergillus fumigatus, seen in two large general hospitals over a ten year period. The study was undertaken to establish the pattern and distribution of pulmonary aspergillosis in this group with particular emphasis on the nature of the underlying disorder ...
G, McCarthy, M X, FitzGerald, P, Keelan
openaire   +2 more sources

Invasive pulmonary aspergillosis

Expert Review of Anti-infective Therapy, 2005
In susceptible patients, invasive aspergillosis has a high incidence and a mortality of up to 80%. The diagnosis of this condition is difficult, especially in the early stages of the disease and, as a consequence, antifungal therapy, despite its expense and toxicity, is often initiated empirically.
S R, Doffman, S G, Agrawal, Jeremy S, Brown   +2 more
openaire   +4 more sources