Novel signaling pathways in pulmonary arterial hypertension (2015 Grover Conference Series) [PDF]
The proliferative endothelial and smooth muscle cell phenotype, inflammation, and pulmonary vascular remodeling are prominent features of pulmonary arterial hypertension (PAH).
Awad, Keytam S.+3 more
core +1 more source
DNA‑Directed Assembly of Photonic Nanomaterials for Diagnostic and Therapeutic Applications
DNA‐directed assembly offers a powerful strategy for constructing structured photonic nanomaterials with precise spatial control. This review provides a comprehensive overview of recent advancements in DNA‐assembled photonic nanomaterials for diagnostics and therapeutics, highlighting key design principles, functionalization strategies, and optical ...
Longjiang Ding+5 more
wiley +1 more source
Global dynamical model of the cardiovascular system [PDF]
Blood system functions are very diverse and important for most processes in human organism. One of its primary functions is matter transport among different parts of the organism including tissue supplying with oxygen, carbon dioxide excretion, drug propagation etc. Forecasting of these processes under normal conditions and in the presence of different
arxiv
Pathophysiologic correlates of exercise intolerance in adults with pulmonary hypertension and congenital heart disease [PDF]
Imperial Users ...
Diller , Gerhard-Paul+1 more
core
Response to pulmonary arterial hypertension drug therapies in patients with pulmonary arterial hypertension and cardiovascular risk factors. [PDF]
The age at diagnosis of pulmonary arterial hypertension (PAH) and the prevalence of cardiovascular (CV) risk factors are increasing. We sought to determine whether the response to drug therapy was influenced by CV risk factors in PAH patients. We studied
Charalampopoulos, A+9 more
core +1 more source
Additive manufacturing, specifically fused deposition modeling, offers an innovative approach to creating 3D‐printed variable orifice flowmeters with integrated temperature compensation. Using carbon‐black TPU, the primary component (a variable orifice) and the secondary element (a diaphragm pressure sensor) are fabricated.
Vincenzo Saroli+2 more
wiley +1 more source
Alteration of Extracellular Superoxide Dismutase in Idiopathic Pulmonary Arterial Hypertension
Background: Superoxide dismutases (SODs) are an important family of antioxidant enzymes that modulate reactive oxygen species levels. It is largely unknown which SOD isoform(s) change in vivo in idiopathic pulmonary arterial hypertension (IPAH) patients ...
Rui Zhang+10 more
doaj +1 more source
Use of mathematical modeling to study pressure regimes in normal and Fontan blood flow circulations [PDF]
We develop two mathematical lumped parameter models for blood pressure distribution in the Fontan blood flow circulation: an ODE based spatially homogeneous model and a PDE based spatially inhomogeneous model. We present numerical simulations of the cardiac pressure-volume cycle and study the effect of pulmonary resistance on cardiac output. We analyze
arxiv
Exercise stress echocardiography of the pulmonary circulation: limits of normal and sex differences.
BACKGROUND Exercise stress echocardiography has not been recommended in the diagnostic workup of pulmonary hypertension because of insufficient certainty about feasibility and limits of normal.
P. Argiento+7 more
semanticscholar +1 more source
On the Relentless Pursuit of an Oral Insulin Delivery System: How Far is Too Far?
Injectable insulin preparations have far outpaced oral ones by virtue of adequate bioavailability and are driven by innovations, including insulin pumps, real‐time blood glucose monitoring, and artificial intelligence. In contrast, oral insulin delivery systems, including nanomedicines, continue to struggle and lag due to varied reasons.
Sourav Bhattacharjee
wiley +1 more source