Results 181 to 190 of about 392,188 (298)

Tumor‐Induced Splenic Remodeling: Mechanisms of Systemic Immunosuppression and Emerging Therapeutic Opportunities

Advanced Science, EarlyView.
ABSTRACT Despite the transformative impact of cancer immunotherapies such as immune checkpoint blockade, durable clinical responses remain limited. Increasing evidence indicates that antitumor immunity is governed not only by the tumor microenvironment, but also by systemic immune regulation mediated by peripheral immune organs. Among these, the spleen
Yuehua Liu, Xiaoqian Nie, Xiaofei Gao
wiley   +1 more source

The golden ratio in the pulmonary circulation in patients with heart failure and cardiogenic shock. [PDF]

Physiol Rep
Lim HS, Yim IHW.
europepmc   +1 more source

Hemodynamically Unloading the Distal Pulmonary Circulation in Pulmonary Hypertension: A Modeling Study. [PDF]

J Biomech Eng, 2022
Walter R, Hunter K, Stenmark K, Kheyfets VO.   +3 more
europepmc   +1 more source

Pulmonary Circulation [PDF]

Respirology, 2015
openaire   +1 more source

Redox‐Responsive Polymeric Nanocapsules for Enhanced Tumor‐Targeted Delivery of Antimicrobial Peptides

Advanced Science, EarlyView.
This study presents a modular redox‐responsive nanocapsule platform that enables enhanced tumor‐targeted delivery of antimicrobial peptides. Using melittin as an example, the system achieves controlled activation within the tumor microenvironment, improving intratumoral accumulation while minimizing systemic toxicity.
Lin Tang, Yajian Li, Xiaoyin Lv, Jianmei Guo, Yijia Zhang, Yuqi Lin, Kaili Nie, Jian Zeng, Ming Zhang, Qiong Dai   +9 more
wiley   +1 more source

Evaluation of the impact of pulmonary circulation, particularly pulmonary vascular resistance, in patients with idiopathic pulmonary fibrosis: an exploratory study. [PDF]

BMC Pulm Med
Tanaka Y, Okamura K, Kaburaki S, Tanaka T, Miyanaga A, Taniuchi N, Kamio K, Kasahara K, Seike M.   +8 more
europepmc   +1 more source

Does the presence of systemic artery-pulmonary circulation shunt during bronchial arterial embolization increase the recurrence of noncancer-related hemoptysis? A retrospective cohort study. [PDF]

Respir Res, 2023
Yan HT, Lu GD, Liu J, Liu S, Shi HB, Zhou CG, Zu QQ.   +6 more
europepmc   +1 more source

PRMT5/Sohlh2/Sirt1 Signaling Pathway in Vascular Endothelial Cells Modulates Lung Metastasis of Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
The cover image shows that vascular endothelial cells play an important role in lung metastasis of TNBC. Endothelial Sohlh2 acts as a gatekeeper against TNBC lung metastasis by limiting endothelial activation and tumor cell passage. PRMT5 reduces Sohlh2 stability, weakening this protective barrier.
Ruihong Zhang, Fengqin Wang, Lanlan Liu, Qi Zhang, Xiaoning Huo, Yanhui Nan, Yanli Dong, Yunling Xiao, Jing Hao   +8 more
wiley   +1 more source

Restrictive Atrial Communication in Tricuspid Atresia With Minimal Duct-Dependent Pulmonary Circulation in a Newborn. [PDF]

JACC Case Rep
Román CM, Fuentes JE, Joubert LM, Ureña Velásquez P, Toribio Acosta J.   +4 more
europepmc   +1 more source

Impact of Right Ventricular-Pulmonary Circulation Coupling on Mortality in SARS-CoV-2 Infection. [PDF]

J Am Heart Assoc, 2022
Bursi F, Santangelo G, Barbieri A, Vella AM, Toriello F, Valli F, Sansalone D, Carugo S, Guazzi M.   +8 more
europepmc   +1 more source