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Invasive haemodynamic evaluation of the pulmonary circulation in pulmonary hypertension.
Swiss medical weekly, 2017 The term pulmonary hypertension refers to a serious condition characterised by high pulmonary vascular pressure, mainly as a consequence of various cardiac and respiratory diseases. Current clinical classification of pulmonary hypertension considers five
A. Pagnamenta +4 more
semanticscholar +1 more source
Nitric Oxide in Experimental Pulmonary Embolism [PDF]
, 2010 Nitric oxide (NO) is an important modulator of the pulmonary circulation both at basal state and in pulmonary hypertension. Low levels of NO are detectable in exhaled gas which is believed to mirror pulmonary NO formation and elimination.
Nilsson, Kristofer F
core +2 more sources
Frontiers in Pharmacology, 2023 Introduction: Pulmonary arterial hypertension (PAH) is a rare and progressive disease. Some patients treated with phosphodiesterase type 5 inhibitors (PDE-5is) fail to reach treatment goals. As a novel soluble guanylate cyclase agonist, riociguat acts on
Yu-Yang Liu +11 more
doaj +1 more source
Numerical predictions of shear stress and cyclic stretch in the healthy pulmonary vasculature [PDF]
arXiv, 2021 Isolated post-capillary pulmonary hypertension (Ipc-PH) occurs due to left heart failure, which contributes to 1 out of every 9 deaths in the United States. In some patients, through unknown mechanisms, Ipc-PH transitions to combined pre-/post-capillary PH (Cpc-PH), diagnosed by an increase in pulmonary vascular resistance and associated with a ...
arxiv
Kardiologia polska, 2015 Right heart catheterisation (RHC) is the 'gold standard' for haemodynamic assessment of the pulmonary circulation. For the diagnosis of pulmonary hypertension (PH), the guidelines of the European Society of Cardiology require a mean pulmonary arterial ...
M. Kurzyna +9 more
semanticscholar +1 more source
Quantification of Bronchial Circulation Perfusion in Rats [PDF]
, 2004 The bronchial circulation is thought to be the primary blood supply for pulmonary carcinomas. Thus, we have developed a method for imaging and quantifying changes in perfusion in the rat lung due to development of the bronchial circulation.
Clough, Anne V. +5 more
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11,12-EET stimulates the association of BK channel α and β(1) subunits in mitochondria to induce pulmonary vasoconstriction [PDF]
, 2012 In the systemic circulation, 11,12-epoxyeicosatrienoic acid (11,12-EET) elicits nitric oxide (NO)- and prostacyclin-independent vascular relaxation, partially through the activation of large conductance Ca2+-activated potassium (BK) channels. However, in
Daiber, Andreas +6 more
core +5 more sources
Pulmonary Vascular Reserve and Aerobic Exercise Capacity [PDF]
, 2019 Pulmonary circulation has long been known to have specific proprieties of recruitment and distention to keep the hemodynamic pressure low even when facing very high blood flow.
Faoro, Vitalie, Forton, Kevin
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Redox Regulation of Ion Channels in the Pulmonary Circulation
Antioxidants and Redox Signaling, 2015 Significance: The pulmonary circulation is a low-pressure, low-resistance, highly compliant vasculature. In contrast to the systemic circulation, it is not primarily regulated by a central nervous control mechanism.
A. Olschewski, E. Weir
semanticscholar +1 more source
Absence of reflex vascular responses from the intrapulmonary circulation in anaesthetised dogs [PDF]
, 2000 The aim of this investigation was to determine whether reflex cardiovascular responses were obtained to localised distension of the intrapulmonary arterial and venous circulations in a preparation in which the stimuli to other major reflexogenic areas ...
Drinkhill, M.J. +3 more
core +1 more source