Results 41 to 50 of about 2,151,759 (386)

Short-term hemodynamic effects of apelin in patients with pulmonary arterial hypertension [PDF]

open access: yes, 2018
Apelin agonism causes systemic vasodilatation and increased cardiac contractility in humans, and improves pulmonary arterial hypertension (PAH) in animal models.
Alastalo   +23 more
core   +4 more sources

Efficacy and safety of riociguat replacing PDE-5is for patients with pulmonary arterial hypertension: A systematic review and meta-analysis

open access: yesFrontiers in Pharmacology, 2023
Introduction: Pulmonary arterial hypertension (PAH) is a rare and progressive disease. Some patients treated with phosphodiesterase type 5 inhibitors (PDE-5is) fail to reach treatment goals. As a novel soluble guanylate cyclase agonist, riociguat acts on
Yu-Yang Liu   +11 more
doaj   +1 more source

The right ventricle: interaction with the pulmonary circulation

open access: yesCritical Care, 2016
The primary role of the right ventricle (RV) is to deliver all the blood it receives per beat into the pulmonary circulation without causing right atrial pressure to rise.
M. Pinsky
semanticscholar   +1 more source

Impact of Parthanatos on the Increased Risk of Onset and Mortality in Male Patients With Pulmonary Hypertension

open access: yesAmerican Journal of Men's Health, 2021
There have been no studies as to whether parthanatos, a poly (adenosine diphosphate-ribose) polymerase-1 (PARP-1)-dependent and apoptosis-inducing factor (AIF)-mediated caspase-independent programmed cell death, is present in pulmonary hypertension (PH).
Zhen-Chun Lv MD   +7 more
doaj   +1 more source

Invasive haemodynamic evaluation of the pulmonary circulation in pulmonary hypertension.

open access: yesSwiss medical weekly, 2017
The term pulmonary hypertension refers to a serious condition characterised by high pulmonary vascular pressure, mainly as a consequence of various cardiac and respiratory diseases. Current clinical classification of pulmonary hypertension considers five
A. Pagnamenta   +4 more
semanticscholar   +1 more source

Physiological and clinical consequences of relief of right ventricular outflow tract obstruction late after repair of congenital heart defects. [PDF]

open access: yes, 2006
BACKGROUND: Right ventricular outflow tract obstruction (RVOTO) is a common problem after repair of congenital heart disease. Percutaneous pulmonary valve implantation (PPVI) can treat this condition without consequent pulmonary regurgitation or ...
Bonhoeffer, P   +10 more
core   +1 more source

The role of prolactin/vasoinhibins in cardiovascular diseases

open access: yesAnimal Models and Experimental Medicine, 2023
Prolactin (PRL) is a polypeptide hormone that is mainly synthesized and secreted by the lactotroph cells of the pituitary. There are two main isoforms of PRL: 23‐kDa PRL (named full‐length PRL) and vasoinhibins (including 5.6–18 kDa fragments).
Hui Zhao   +10 more
doaj   +1 more source

Absence of reflex vascular responses from the intrapulmonary circulation in anaesthetised dogs [PDF]

open access: yes, 2000
The aim of this investigation was to determine whether reflex cardiovascular responses were obtained to localised distension of the intrapulmonary arterial and venous circulations in a preparation in which the stimuli to other major reflexogenic areas ...
Drinkhill, M.J.   +3 more
core   +1 more source

Prognostic Value of Follicle-Stimulating Hormone Levels in Predicting Survival in Men With Idiopathic Pulmonary Arterial Hypertension

open access: yesAmerican Journal of Men's Health, 2022
The objective of the study was to assess the association between changes in plasma follicle-stimulating hormone (FSH) and the potential effect on idiopathic pulmonary arterial hypertension (IPAH) in male patients.
Qian Wang   +5 more
doaj   +1 more source

Transient but not genetic loss of miR-451 attenuates the development of pulmonary arterial hypertension [PDF]

open access: yes, 2013
<b>Rationale:</b> MicroRNAs are small non-coding RNAs involved in the regulation of gene expression and have recently been implicated in the development of pulmonary arterial hypertension (PAH).
Baker, Andrew H.   +5 more
core   +2 more sources

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