Results 41 to 50 of about 2,151,759 (386)
Short-term hemodynamic effects of apelin in patients with pulmonary arterial hypertension [PDF]
Apelin agonism causes systemic vasodilatation and increased cardiac contractility in humans, and improves pulmonary arterial hypertension (PAH) in animal models.
Alastalo +23 more
core +4 more sources
Introduction: Pulmonary arterial hypertension (PAH) is a rare and progressive disease. Some patients treated with phosphodiesterase type 5 inhibitors (PDE-5is) fail to reach treatment goals. As a novel soluble guanylate cyclase agonist, riociguat acts on
Yu-Yang Liu +11 more
doaj +1 more source
The right ventricle: interaction with the pulmonary circulation
The primary role of the right ventricle (RV) is to deliver all the blood it receives per beat into the pulmonary circulation without causing right atrial pressure to rise.
M. Pinsky
semanticscholar +1 more source
There have been no studies as to whether parthanatos, a poly (adenosine diphosphate-ribose) polymerase-1 (PARP-1)-dependent and apoptosis-inducing factor (AIF)-mediated caspase-independent programmed cell death, is present in pulmonary hypertension (PH).
Zhen-Chun Lv MD +7 more
doaj +1 more source
Invasive haemodynamic evaluation of the pulmonary circulation in pulmonary hypertension.
The term pulmonary hypertension refers to a serious condition characterised by high pulmonary vascular pressure, mainly as a consequence of various cardiac and respiratory diseases. Current clinical classification of pulmonary hypertension considers five
A. Pagnamenta +4 more
semanticscholar +1 more source
Physiological and clinical consequences of relief of right ventricular outflow tract obstruction late after repair of congenital heart defects. [PDF]
BACKGROUND: Right ventricular outflow tract obstruction (RVOTO) is a common problem after repair of congenital heart disease. Percutaneous pulmonary valve implantation (PPVI) can treat this condition without consequent pulmonary regurgitation or ...
Bonhoeffer, P +10 more
core +1 more source
The role of prolactin/vasoinhibins in cardiovascular diseases
Prolactin (PRL) is a polypeptide hormone that is mainly synthesized and secreted by the lactotroph cells of the pituitary. There are two main isoforms of PRL: 23‐kDa PRL (named full‐length PRL) and vasoinhibins (including 5.6–18 kDa fragments).
Hui Zhao +10 more
doaj +1 more source
Absence of reflex vascular responses from the intrapulmonary circulation in anaesthetised dogs [PDF]
The aim of this investigation was to determine whether reflex cardiovascular responses were obtained to localised distension of the intrapulmonary arterial and venous circulations in a preparation in which the stimuli to other major reflexogenic areas ...
Drinkhill, M.J. +3 more
core +1 more source
The objective of the study was to assess the association between changes in plasma follicle-stimulating hormone (FSH) and the potential effect on idiopathic pulmonary arterial hypertension (IPAH) in male patients.
Qian Wang +5 more
doaj +1 more source
Transient but not genetic loss of miR-451 attenuates the development of pulmonary arterial hypertension [PDF]
<b>Rationale:</b> MicroRNAs are small non-coding RNAs involved in the regulation of gene expression and have recently been implicated in the development of pulmonary arterial hypertension (PAH).
Baker, Andrew H. +5 more
core +2 more sources

