Results 21 to 30 of about 208,145 (265)
Fulvine and the pulmonary circulation [PDF]
The pyrrolizidine alkaloid, fulvine, is now accepted as a major cause of veno-occlusive disease of the liver in the West Indies, where it is ingested as a decoction of the plant Crotalaria fulva in bush tea. Fulvine is similar in chemical structure to monocrotaline, which is known to cause pulmonary hypertension in rats.
J M, Kay +4 more
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Exosomal circular RNAs: Biogenesis, effect, and application in cardiovascular diseases
As natural nanoparticles, exosomes regulate a wide range of biological processes via modulation of its components, including circular RNAs (circRNAs).
Xiaoyi Hu +15 more
doaj +1 more source
Circular RNAs in pulmonary hypertension: Emerging biological concepts and potential mechanism
Circular RNAs (circRNAs) are endogenous RNAs with a covalently closed single‐stranded transcript. They are a novel class of genomic regulators that are linked to many important development and disease processes and are being pursued as clinical and ...
Qian Wang +6 more
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Background We recently demonstrated that circGSAP was diminished in lung tissues from patients with pulmonary arterial hypertension and in hypoxia-induced pulmonary microvascular endothelial cells (PMECs).
Yuanyuan Sun +11 more
doaj +1 more source
Pulmonary fibrosis (PF) and pulmonary hypertension (PH) have common pathophysiological features, such as the significant remodeling of pulmonary parenchyma and vascular wall.
Hui Zhao +13 more
doaj +1 more source
Megakaryocytes in the Pulmonary Circulation [PDF]
Abstract The streptolysin 0 hemolysis method for isolation of cancer cells in the blood was employed for direct observations of the incidence and some characteristics of circulating megakaryocytes. In a series of 168 patients, circulating megakaryocytes were found in 77 per cent of the blood samples.
T M, SCHEININ, A P, KOIVUNIEMI
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Biology and function of pericytes in the vascular microcirculation
Pericytes are the main cellular components of tiny arteries and capillaries. Studies have found that pericytes can undergo morphological contraction or relaxation under stimulation by cytokines, thus affecting the contraction and relaxation of ...
Yue Wu +12 more
doaj +1 more source
ObjectiveWhether exercise-induced venous-to-systemic shunt (EIS) during cardiopulmonary exercise testing (CPET) has different manifestations or characteristics in idiopathic pulmonary arterial hypertension (IPAH) and chronic thromboembolic pulmonary ...
Shang Wang +15 more
doaj +1 more source
Background To study the oxygen uptake efficiency and determine usefulness of submaximal parameters of oxygen uptake in systemic lupus erythematosus associated pulmonary arterial hypertension (SLE PAH) on performing a cardiopulmonary exercise test (CPET).
Bigyan Pudasaini +13 more
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Discovery of the pulmonary circulation [PDF]
A reply to a reply: From ancient Persia (before 637 AD) to William Harvey (17th Century AD) We read with the great interest the response of Bestett and Couto1 to our last publication on the discovery of pulmonary circulation by ancient Persians.2 The authors claimed that the credit for the discovery of the pulmonary circulation should be given to ...
Arman, Zargaran, Hamed, Arezaei
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