Results 21 to 30 of about 395,005 (295)

The marginated pool [PDF]

open access: yes, 2002
The pulmonary circulation harbors a large intravascular reservoir of leukocytes refered to as the Marginated Pool. This marginated pool is balanced by propeling and retaining forces acting on leukocytes during their passage through the pulmonary ...
Goetz, Alwin Eduard   +1 more
core   +1 more source

Exosomal circular RNAs: Biogenesis, effect, and application in cardiovascular diseases

open access: yesFrontiers in Cell and Developmental Biology, 2022
As natural nanoparticles, exosomes regulate a wide range of biological processes via modulation of its components, including circular RNAs (circRNAs).
Xiaoyi Hu   +15 more
doaj   +1 more source

Circular RNAs in pulmonary hypertension: Emerging biological concepts and potential mechanism

open access: yesAnimal Models and Experimental Medicine, 2022
Circular RNAs (circRNAs) are endogenous RNAs with a covalently closed single‐stranded transcript. They are a novel class of genomic regulators that are linked to many important development and disease processes and are being pursued as clinical and ...
Qian Wang   +6 more
doaj   +1 more source

CircGSAP regulates the cell cycle of pulmonary microvascular endothelial cells via the miR-942-5p sponge in pulmonary hypertension

open access: yesFrontiers in Cell and Developmental Biology, 2022
Background We recently demonstrated that circGSAP was diminished in lung tissues from patients with pulmonary arterial hypertension and in hypoxia-induced pulmonary microvascular endothelial cells (PMECs).
Yuanyuan Sun   +11 more
doaj   +1 more source

Bronchial Circulation Angiogenesis in the Rat Quantified with SPECT and Micro-CT [PDF]

open access: yes, 2008
Introduction As pulmonary artery obstruction results in proliferation of the bronchial circulation in a variety of species, we investigated this angiogenic response using single photon emission computed tomography (SPECT) and micro-CT.
Clough, Anne V.   +5 more
core   +2 more sources

Differences in disease severity and prognosis of exercise-induced right-to-left shunt between idiopathic pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension patients

open access: yesFrontiers in Cardiovascular Medicine, 2022
ObjectiveWhether exercise-induced venous-to-systemic shunt (EIS) during cardiopulmonary exercise testing (CPET) has different manifestations or characteristics in idiopathic pulmonary arterial hypertension (IPAH) and chronic thromboembolic pulmonary ...
Shang Wang   +15 more
doaj   +1 more source

Role of prostacyclin in pulmonary hypertension [PDF]

open access: yes, 2014
Date of Acceptance: 11/12/2014 This is an open access article distributed under the terms of the Creative Commons Attribution license CC BY-4.0, which permits unrestricted use, distribution and reproduction in any medium, provided the original work is ...
Ali FY   +8 more
core   +3 more sources

Biology and function of pericytes in the vascular microcirculation

open access: yesAnimal Models and Experimental Medicine, 2023
Pericytes are the main cellular components of tiny arteries and capillaries. Studies have found that pericytes can undergo morphological contraction or relaxation under stimulation by cytokines, thus affecting the contraction and relaxation of ...
Yue Wu   +12 more
doaj   +1 more source

Mesenchymal adenomatous polyposis coli plays critical and diverse roles in regulating lung development. [PDF]

open access: yes, 2015
BackgroundAdenomatous polyposis coli (Apc) is a tumor suppressor that inhibits Wnt/Ctnnb1. Mutations of Apc will not only lead to familial adenomatous polyposis with associated epithelial lesions, but will also cause aggressive fibromatosis in ...
Bellusci, Saverio   +9 more
core   +1 more source

Identification of the shared gene signatures between pulmonary fibrosis and pulmonary hypertension using bioinformatics analysis

open access: yesFrontiers in Immunology, 2023
Pulmonary fibrosis (PF) and pulmonary hypertension (PH) have common pathophysiological features, such as the significant remodeling of pulmonary parenchyma and vascular wall.
Hui Zhao   +13 more
doaj   +1 more source

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